Computational results from the biosynthesis anchor model (adapted from [13]).

<p>Left Panel: The dose-response curve of the effect of dioxin on the biosynthesis rate of hepatic cholesterol is expressed as the percent of remaining activity in comparison with the control. The trendline was matched to fit experimental data (symbols) on mice [<a href="http://www.plo...

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Bibliographic Details
Main Author:	Carla M. Kumbale (15309073) (author)
Other Authors:	Qiang Zhang (45005) (author), Eberhard O. Voit (7377512) (author)
Published:	2025
Subjects:	Medicine Genetics Neuroscience Biotechnology Cancer Science Policy Biological Sciences not elsewhere classified Information Systems not elsewhere classified sex hormone steroidogenesis represent component sub new approach methodology main physiological processes lower biological levels body &# 8217 grained model capturing xlink "> dioxins modeling paradigm enables cholesterol biosynthesis via third anchor model overall health impact multiple health effects modeling paradigm human health template model well documented systemic effects skin rashes reproductive toxicity powerful tool personalized medicine novel adaptation mevalonate pathway menstrual cycle mediated effects liver dysfunction level coarse holistic evaluation greater detail future may dioxins remains developed previously comprehensive understanding cholesterol transport anchor models
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Computational results from the biosynthesis anchor model (adapted from [13]).

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