Figure 2 from Screening FDA-Approved Oncology Drugs with Three-Dimensional Spheroids Identifies Romidepsin as a Therapeutic Candidate for Osteosarcoma

<p>Top hits of initial screen are HDIs, proteasome inhibitors, and topoisomerase inhibitors. <b>A,</b> Screen of FDA-approved oncology drugs on sarcospheres generated from 143B, MG63.3-GFP, and LM7 cell lines. Heatmap shows inhibition of growth in blue and little or no effect in re...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Emily E. Seiden (22436851) (author)
مؤلفون آخرون:	Spencer M. Richardson (22436854) (author), Leah A. Everitt (22436857) (author), Gabrielle J. Knafler (22436860) (author), Alyssa L. Walker (22436863) (author), Venetia A. Whiteside (22436866) (author), Divya Pillutla (22436869) (author), Shrey Ramnath (22436872) (author), Gavin P. Kinsella (22436875) (author), Piper A. Wilburn (22436878) (author), James D. Buschbach (22436881) (author), Deep A. Gandhi (22436884) (author), M. Reza Saadatzadeh (22436887) (author), L. Daniel Wurtz (22436890) (author), Patrick J. Getty (22436893) (author), Sheldon L. Padgett (22436896) (author), Rance M. Gamblin (22436899) (author), Michael O. Childress (22436902) (author), Christopher M. Fulkerson (15090300) (author), Maegan L. Capitano (22436905) (author), Karen E. Pollok (21365488) (author), Christopher D. Collier (21365482) (author), Edward M. Greenfield (22436908) (author)
منشور في:	2025
الموضوعات:	Cancer Tumor Biology Therapeutic Research and Development Methods and Technology Drug Discovery Technologies Screening strategies (assays and chemical libraries) In Vitro Models Of Cancer Progression, Invasion & Metastasis Tumor progression Pediatric Cancers Sarcomas Osteosarcoma Small Molecule Agents
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

Figure 2 from Screening FDA-Approved Oncology Drugs with Three-Dimensional Spheroids Identifies Romidepsin as a Therapeutic Candidate for Osteosarcoma

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