Figure 2 from Screening FDA-Approved Oncology Drugs with Three-Dimensional Spheroids Identifies Romidepsin as a Therapeutic Candidate for Osteosarcoma

<p>Top hits of initial screen are HDIs, proteasome inhibitors, and topoisomerase inhibitors. <b>A,</b> Screen of FDA-approved oncology drugs on sarcospheres generated from 143B, MG63.3-GFP, and LM7 cell lines. Heatmap shows inhibition of growth in blue and little or no effect in re...

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主要作者:	Emily E. Seiden (22436851) (author)
其他作者:	Spencer M. Richardson (22436854) (author), Leah A. Everitt (22436857) (author), Gabrielle J. Knafler (22436860) (author), Alyssa L. Walker (22436863) (author), Venetia A. Whiteside (22436866) (author), Divya Pillutla (22436869) (author), Shrey Ramnath (22436872) (author), Gavin P. Kinsella (22436875) (author), Piper A. Wilburn (22436878) (author), James D. Buschbach (22436881) (author), Deep A. Gandhi (22436884) (author), M. Reza Saadatzadeh (22436887) (author), L. Daniel Wurtz (22436890) (author), Patrick J. Getty (22436893) (author), Sheldon L. Padgett (22436896) (author), Rance M. Gamblin (22436899) (author), Michael O. Childress (22436902) (author), Christopher M. Fulkerson (15090300) (author), Maegan L. Capitano (22436905) (author), Karen E. Pollok (21365488) (author), Christopher D. Collier (21365482) (author), Edward M. Greenfield (22436908) (author)
出版:	2025
主題:	Cancer Tumor Biology Therapeutic Research and Development Methods and Technology Drug Discovery Technologies Screening strategies (assays and chemical libraries) In Vitro Models Of Cancer Progression, Invasion & Metastasis Tumor progression Pediatric Cancers Sarcomas Osteosarcoma Small Molecule Agents
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Figure 2 from Screening FDA-Approved Oncology Drugs with Three-Dimensional Spheroids Identifies Romidepsin as a Therapeutic Candidate for Osteosarcoma

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