Processed snRNA-seq data from wild-type and <i>Pink1</i>-deficient mouse gut

Processed snRNA-seq data from wild-type and <i>Pink1</i>-deficient mouse gut

<p dir="ltr">This Figshare record contains processed single-nucleus RNA-seq (snRNA-seq) objects and analysis code used in the study of wild-type (WT) and <i>Pink1</i> knockout (<i>Pink1</i> KO) mouse gut.</p><p dir="ltr">Files:<br>&...

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Hlavní autor: Muhammad Junaid (14524523) (author)
Další autoři: Soo Jung Park (748802) (author), Yiseul Bae (17001093) (author), Eun Jeong Lee (7400936) (author), Su Bin Lim (7112791) (author)
Vydáno: 2025
Témata:
Genomics and transcriptomics
Sequence analysis
Gene mapping
Single-nucleus RNA-seq data
gut tissue damage
PINK1 knockout rat
label transfer
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Shrnutí:<p dir="ltr">This Figshare record contains processed single-nucleus RNA-seq (snRNA-seq) objects and analysis code used in the study of wild-type (WT) and <i>Pink1</i> knockout (<i>Pink1</i> KO) mouse gut.</p><p dir="ltr">Files:<br><b>WT_Pink1KO.rds</b>: Seurat object containing QC-filtered and processed nuclei from WT and <i>Pink1</i> KO gut samples.<br><b>Validation_WT_Pink1KO.rds</b>: Seurat object after label transfer and validation using an external public reference dataset, including final cell-type annotations.<br><b>Code.R</b>: R script used for preprocessing, quality control, integration of WT and <i>Pink1</i> KO samples, label transfer from the public reference dataset, and generation of the main figures.</p>

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