Simplification of Boolean networks in general.
<p>In panel (A) is presented the Boolean network (E. 13) with its computational solution calculated with BoolNet [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0319240#pone.0319240.ref016" target="_blank">16</a>] and GINSIM [<a href=&q...
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2025
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| _version_ | 1852016657797480448 |
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| author | Antonio Bensussen (5800739) |
| author2 | J. Arturo Arciniega-González (22238618) Elena R. Álvarez-Buylla (3265740) Juan Carlos Martínez-García (3755350) |
| author2_role | author author author |
| author_facet | Antonio Bensussen (5800739) J. Arturo Arciniega-González (22238618) Elena R. Álvarez-Buylla (3265740) Juan Carlos Martínez-García (3755350) |
| author_role | author |
| dc.creator.none.fl_str_mv | Antonio Bensussen (5800739) J. Arturo Arciniega-González (22238618) Elena R. Álvarez-Buylla (3265740) Juan Carlos Martínez-García (3755350) |
| dc.date.none.fl_str_mv | 2025-09-12T17:48:39Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pone.0319240.g007 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Simplification_of_Boolean_networks_in_general_/30115916 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Genetics Developmental Biology Cancer Computational Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Physical Sciences not elsewhere classified xlink "> characterizing produce characteristic properties asynchronous scheme generates dynamical properties found canonical form might asynchronous update schemes solve boolean networks biological systems modeled synchronous update scheme update schemes canonical form boolean networks update order biological system boolean network synchronous scheme point attractors particular case new possibilities matrix equation mathematical terms markov chains kolmogorov equation composed together analytical approach also discovered |
| dc.title.none.fl_str_mv | Simplification of Boolean networks in general. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>In panel (A) is presented the Boolean network (E. 13) with its computational solution calculated with BoolNet [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0319240#pone.0319240.ref016" target="_blank">16</a>] and GINSIM [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0319240#pone.0319240.ref017" target="_blank">17</a>]. In panel (B) is presented the Boolean function , obtained by using the logic rules of (E. 13). In panel (C) is shown the transformation of to integers. In panel (D) is presented the function with all their interactions sent directly to the attractor to which they naturally converge, and in panel (E) is shown the conversion of this function to binary numbers. Finally, in panel (F) is shown the network generated from , which corresponds to the network (E. 14). Note that (E. 14) is a simplified version of (E. 13).</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_17c4e459f6e045ad9dfbbc53c87ce751 |
| identifier_str_mv | 10.1371/journal.pone.0319240.g007 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30115916 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Simplification of Boolean networks in general.Antonio Bensussen (5800739)J. Arturo Arciniega-González (22238618)Elena R. Álvarez-Buylla (3265740)Juan Carlos Martínez-García (3755350)GeneticsDevelopmental BiologyCancerComputational BiologyBiological Sciences not elsewhere classifiedMathematical Sciences not elsewhere classifiedPhysical Sciences not elsewhere classifiedxlink "> characterizingproduce characteristic propertiesasynchronous scheme generatesdynamical properties foundcanonical form mightasynchronous update schemessolve boolean networksbiological systems modeledsynchronous update schemeupdate schemescanonical formboolean networksupdate orderbiological systemboolean networksynchronous schemepoint attractorsparticular casenew possibilitiesmatrix equationmathematical termsmarkov chainskolmogorov equationcomposed togetheranalytical approachalso discovered<p>In panel (A) is presented the Boolean network (E. 13) with its computational solution calculated with BoolNet [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0319240#pone.0319240.ref016" target="_blank">16</a>] and GINSIM [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0319240#pone.0319240.ref017" target="_blank">17</a>]. In panel (B) is presented the Boolean function , obtained by using the logic rules of (E. 13). In panel (C) is shown the transformation of to integers. In panel (D) is presented the function with all their interactions sent directly to the attractor to which they naturally converge, and in panel (E) is shown the conversion of this function to binary numbers. Finally, in panel (F) is shown the network generated from , which corresponds to the network (E. 14). Note that (E. 14) is a simplified version of (E. 13).</p>2025-09-12T17:48:39ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pone.0319240.g007https://figshare.com/articles/figure/Simplification_of_Boolean_networks_in_general_/30115916CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/301159162025-09-12T17:48:39Z |
| spellingShingle | Simplification of Boolean networks in general. Antonio Bensussen (5800739) Genetics Developmental Biology Cancer Computational Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Physical Sciences not elsewhere classified xlink "> characterizing produce characteristic properties asynchronous scheme generates dynamical properties found canonical form might asynchronous update schemes solve boolean networks biological systems modeled synchronous update scheme update schemes canonical form boolean networks update order biological system boolean network synchronous scheme point attractors particular case new possibilities matrix equation mathematical terms markov chains kolmogorov equation composed together analytical approach also discovered |
| status_str | publishedVersion |
| title | Simplification of Boolean networks in general. |
| title_full | Simplification of Boolean networks in general. |
| title_fullStr | Simplification of Boolean networks in general. |
| title_full_unstemmed | Simplification of Boolean networks in general. |
| title_short | Simplification of Boolean networks in general. |
| title_sort | Simplification of Boolean networks in general. |
| topic | Genetics Developmental Biology Cancer Computational Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Physical Sciences not elsewhere classified xlink "> characterizing produce characteristic properties asynchronous scheme generates dynamical properties found canonical form might asynchronous update schemes solve boolean networks biological systems modeled synchronous update scheme update schemes canonical form boolean networks update order biological system boolean network synchronous scheme point attractors particular case new possibilities matrix equation mathematical terms markov chains kolmogorov equation composed together analytical approach also discovered |