Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis

<p>Dual inhibition of ENG and MEK efficiently blocks ENG-Smad1/5 and MAPK/ERK pathway activation in ST88-14 cells.</p>

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Autor principal: Teresa González-Muñoz (16797866) (author)
Outros Autores: Angela Di Giannatale (16797869) (author), Susana García-Silva (16797872) (author), Vanesa Santos (16797875) (author), Sara Sánchez-Redondo (16797878) (author), Claudia Savini (16797881) (author), Osvaldo Graña-Castro (16797884) (author), Carmen Blanco-Aparicio (16797887) (author), Suzanne Fischer (16797890) (author), Olivier De Wever (16797893) (author), Edgar Creus-Bachiller (15088596) (author), Sara Ortega-Bertran (15088605) (author), David J. Pisapia (14139052) (author), Jose L. Rodríguez-Peralto (16797896) (author), Juana Fernández-Rodríguez (15088593) (author), Cleofé Romagosa Pérez-Portabella (16797899) (author), Rita Alaggio (15063322) (author), Maria Serena Benassi (16797902) (author), Laura Pazzaglia (16797905) (author), Katia Scotlandi (14954989) (author), Nancy Ratner (16797908) (author), Kaleb Yohay (11099577) (author), Charles P. Theuer (16797911) (author), Héctor Peinado (15187663) (author)
Publicado em: 2025
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author Teresa González-Muñoz (16797866)
author2 Angela Di Giannatale (16797869)
Susana García-Silva (16797872)
Vanesa Santos (16797875)
Sara Sánchez-Redondo (16797878)
Claudia Savini (16797881)
Osvaldo Graña-Castro (16797884)
Carmen Blanco-Aparicio (16797887)
Suzanne Fischer (16797890)
Olivier De Wever (16797893)
Edgar Creus-Bachiller (15088596)
Sara Ortega-Bertran (15088605)
David J. Pisapia (14139052)
Jose L. Rodríguez-Peralto (16797896)
Juana Fernández-Rodríguez (15088593)
Cleofé Romagosa Pérez-Portabella (16797899)
Rita Alaggio (15063322)
Maria Serena Benassi (16797902)
Laura Pazzaglia (16797905)
Katia Scotlandi (14954989)
Nancy Ratner (16797908)
Kaleb Yohay (11099577)
Charles P. Theuer (16797911)
Héctor Peinado (15187663)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Teresa González-Muñoz (16797866)
Angela Di Giannatale (16797869)
Susana García-Silva (16797872)
Vanesa Santos (16797875)
Sara Sánchez-Redondo (16797878)
Claudia Savini (16797881)
Osvaldo Graña-Castro (16797884)
Carmen Blanco-Aparicio (16797887)
Suzanne Fischer (16797890)
Olivier De Wever (16797893)
Edgar Creus-Bachiller (15088596)
Sara Ortega-Bertran (15088605)
David J. Pisapia (14139052)
Jose L. Rodríguez-Peralto (16797896)
Juana Fernández-Rodríguez (15088593)
Cleofé Romagosa Pérez-Portabella (16797899)
Rita Alaggio (15063322)
Maria Serena Benassi (16797902)
Laura Pazzaglia (16797905)
Katia Scotlandi (14954989)
Nancy Ratner (16797908)
Kaleb Yohay (11099577)
Charles P. Theuer (16797911)
Héctor Peinado (15187663)
author_role author
dc.creator.none.fl_str_mv Teresa González-Muñoz (16797866)
Angela Di Giannatale (16797869)
Susana García-Silva (16797872)
Vanesa Santos (16797875)
Sara Sánchez-Redondo (16797878)
Claudia Savini (16797881)
Osvaldo Graña-Castro (16797884)
Carmen Blanco-Aparicio (16797887)
Suzanne Fischer (16797890)
Olivier De Wever (16797893)
Edgar Creus-Bachiller (15088596)
Sara Ortega-Bertran (15088605)
David J. Pisapia (14139052)
Jose L. Rodríguez-Peralto (16797896)
Juana Fernández-Rodríguez (15088593)
Cleofé Romagosa Pérez-Portabella (16797899)
Rita Alaggio (15063322)
Maria Serena Benassi (16797902)
Laura Pazzaglia (16797905)
Katia Scotlandi (14954989)
Nancy Ratner (16797908)
Kaleb Yohay (11099577)
Charles P. Theuer (16797911)
Héctor Peinado (15187663)
dc.date.none.fl_str_mv 2025-11-25T13:28:17Z
dc.identifier.none.fl_str_mv 10.1158/1078-0432.30709242
dc.relation.none.fl_str_mv https://figshare.com/articles/figure/Suppl_Figure_6_from_Endoglin_a_Novel_Biomarker_and_Therapeutical_Target_to_Prevent_Malignant_Peripheral_Nerve_Sheath_Tumor_Growth_and_Metastasis/30709242
dc.rights.none.fl_str_mv CC BY
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cancer
Tumor Biology
Therapeutic Research and Development
Methods and Technology
Angiogenesis
Angiogenesis mechanisms
Biological Agents & Therapies
Preclinical Models
Xenograft models
Progression, Invasion & Metastasis
Tumor progression
Sarcomas
dc.title.none.fl_str_mv Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
dc.type.none.fl_str_mv Image
Figure
info:eu-repo/semantics/publishedVersion
image
description <p>Dual inhibition of ENG and MEK efficiently blocks ENG-Smad1/5 and MAPK/ERK pathway activation in ST88-14 cells.</p>
eu_rights_str_mv openAccess
id Manara_17fdf39b52d412105add9994d1174f66
identifier_str_mv 10.1158/1078-0432.30709242
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30709242
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY
spelling Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and MetastasisTeresa González-Muñoz (16797866)Angela Di Giannatale (16797869)Susana García-Silva (16797872)Vanesa Santos (16797875)Sara Sánchez-Redondo (16797878)Claudia Savini (16797881)Osvaldo Graña-Castro (16797884)Carmen Blanco-Aparicio (16797887)Suzanne Fischer (16797890)Olivier De Wever (16797893)Edgar Creus-Bachiller (15088596)Sara Ortega-Bertran (15088605)David J. Pisapia (14139052)Jose L. Rodríguez-Peralto (16797896)Juana Fernández-Rodríguez (15088593)Cleofé Romagosa Pérez-Portabella (16797899)Rita Alaggio (15063322)Maria Serena Benassi (16797902)Laura Pazzaglia (16797905)Katia Scotlandi (14954989)Nancy Ratner (16797908)Kaleb Yohay (11099577)Charles P. Theuer (16797911)Héctor Peinado (15187663)CancerTumor BiologyTherapeutic Research and DevelopmentMethods and TechnologyAngiogenesisAngiogenesis mechanismsBiological Agents & TherapiesPreclinical ModelsXenograft modelsProgression, Invasion & MetastasisTumor progressionSarcomas<p>Dual inhibition of ENG and MEK efficiently blocks ENG-Smad1/5 and MAPK/ERK pathway activation in ST88-14 cells.</p>2025-11-25T13:28:17ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/1078-0432.30709242https://figshare.com/articles/figure/Suppl_Figure_6_from_Endoglin_a_Novel_Biomarker_and_Therapeutical_Target_to_Prevent_Malignant_Peripheral_Nerve_Sheath_Tumor_Growth_and_Metastasis/30709242CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/307092422025-11-25T13:28:17Z
spellingShingle Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
Teresa González-Muñoz (16797866)
Cancer
Tumor Biology
Therapeutic Research and Development
Methods and Technology
Angiogenesis
Angiogenesis mechanisms
Biological Agents & Therapies
Preclinical Models
Xenograft models
Progression, Invasion & Metastasis
Tumor progression
Sarcomas
status_str publishedVersion
title Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
title_full Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
title_fullStr Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
title_full_unstemmed Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
title_short Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
title_sort Suppl. Figure 6 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
topic Cancer
Tumor Biology
Therapeutic Research and Development
Methods and Technology
Angiogenesis
Angiogenesis mechanisms
Biological Agents & Therapies
Preclinical Models
Xenograft models
Progression, Invasion & Metastasis
Tumor progression
Sarcomas