Moderately increased ventricular areas in P7 Katnal2-KO mice and largely normal intracranial brain volumes in P70 Katnal2-KO mice.
<p>(A) Moderately increased areas of lateral ventricles in Katnal2-KO mice at P7, as shown by measurements derived from coronal brain slices. Note that brain areas are not increased at P7. AP axis, anterior-posterior axis. Scale bar, 2 mm. (<i>n</i> = 5 mice [WT], 6 [KO], two-way R...
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| مؤلفون آخرون: | , , , , , , , , , , , , , , , , , , , , , |
| منشور في: |
2024
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| الملخص: | <p>(A) Moderately increased areas of lateral ventricles in Katnal2-KO mice at P7, as shown by measurements derived from coronal brain slices. Note that brain areas are not increased at P7. AP axis, anterior-posterior axis. Scale bar, 2 mm. (<i>n</i> = 5 mice [WT], 6 [KO], two-way RM-ANOVA). (B) Largely normal intracranial brain volumes, with very moderate increases in select brain regions, among Katnal2-KO mice (3 months), as shown by MRI analyses of absolute and relative brain volumes (two-way ANOVA). Note, however, that there are moderate Katnal2-KO-dependent increases some brain regions (one-sample <i>t</i> test). (<i>n</i> = 8 mice [WT], 6 [KO], two-way RM-ANOVA and one-sample <i>t</i> test). Significance is indicated as * (<0.05) or ns (not significant). Statistical results and numerical data values can be found in <b><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002596#pbio.3002596.s009" target="_blank">S1 Data</a></b>.</p> <p>(TIF)</p> |
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