Long-Term Single-Particle Tracking of Membrane Proteins Enabled by Upconversion Alkaline-Earth Nanoprobes
Single-particle tracking (SPT) provides mechanistic insights into individual biomolecules but suffers from the limited photostability of conventional probes. Upconversion SPT (uSPT), employing lanthanide-doped nanoparticles (UCNPs) as probes, enables extended imaging durations; however, its broader...
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2025
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