<i>DANCR</i> is a clinically important MITF and c-MYC regulated lncRNA in human melanoma.

<i>DANCR</i> is a clinically important MITF and c-MYC regulated lncRNA in human melanoma.

<p><b>(A)</b> UCSC genome browser view showing MITF and c-MYC ChIP-seq peaks across the <i>DANCR</i> locus (GRCh37/hg19). <b>(B)</b> MITF and <b>(C)</b> c-MYC regulate <i>DANCR</i> in melanoma. siRNA transfection was used to deplete M...

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Bibliographic Details
Main Author: Stephanie M. E. Jones (12883691) (author)
Other Authors: Elizabeth A. Coe (8195508) (author), Michael Shapiro (80677) (author), Kelli M. Gallacher (22772681) (author), Karen Camargo Sosa (22772684) (author), Nikolas Nikolaou (21103869) (author), Igor Ulitsky (28697) (author), Robert N. Kelsh (42493) (author), Keith W. Vance (8195523) (author)
Published: 2025
Subjects:
Medicine
Cell Biology
Genetics
Molecular Biology
Immunology
Developmental Biology
Cancer
Hematology
Infectious Diseases
Computational Biology
Biological Sciences not elsewhere classified
remains unclear whether
positionally equivalent transcripts
play crucial roles
div >< p
differentiation antagonizing non
regulates genes involved
exert similar roles
lncrna transcription relative
positionally equivalent lncrnas
regulating gene expression
diseases including cancer
rna dancr </
associated lncrnas predicted
syntenic long non
early zebrafish development
human melanoma oncogene
long non
dancr </
associated lncrna
melanoma oncogene
syntenic regions
similar regions
processes involved
mitfa </
enriched lncrna
zebrafish development
organismal development
embryonic development
critical lncrnas
melanoma patients
identified melanoma
human melanoma
zebrafish genomes
work suggests
vertebrate genomes
transcriptionally activated
regulate human
neighbouring protein
functional investigation
distant species
developing embryo
controls cancer
cell death
>, expressed
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