Impact of multiunit merging on neural information encoding.

Impact of multiunit merging on neural information encoding.

<p>Multiunit merging, a common artifact in spike sorting, combines spikes from multiple neurons into a single “putative neuron.” This inflates firing rates—particularly masking low firing rate neurons—and obscures their distinct information-encoding properties. <b>(A)</b> Schematic...

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Bibliographic Details
Main Author: Daniel Suárez-Barrera (22676654) (author)
Other Authors: Lucas Bayones (22676657) (author), Norberto Encinas-Rodríguez (22676660) (author), Sergio Parra (22676663) (author), Viktor Monroy (22676666) (author), Sebastián Pujalte (22676669) (author), Bernardo Andrade-Ortega (22676672) (author), Héctor Díaz (22676675) (author), Manuel Alvarez (3468647) (author), Antonio Zainos (22676678) (author), Alessio Franci (143351) (author), Román Rossi-Pool (22676681) (author)
Published: 2025
Subjects:
Cell Biology
Molecular Biology
Neuroscience
Physiology
Biotechnology
Developmental Biology
Science Policy
Space Science
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Information Systems not elsewhere classified
spike sorting pipelines
spike sorting pipeline
seldom spiking neurons
recorded putative neurons
correctly sorted neurons
clustering algorithms responsible
spike sorting makes
reliable spike sorting
umap drastically increases
data analysis techniques
drastically improve
processed data
experimental data
universal practice
precise explorations
neural recordings
neural code
mathematically grounded
fundamentally motivated
extracellular electrophysiology
enables deeper
crucial step
computational cost
ad hoc
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