Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5′-Untranslated Region of SARS-CoV‑2

Throughout the family of coronaviruses, structured RNA elements within the 5′ region of the genome are highly conserved. The fifth stem-loop element from SARS-CoV-2 (5_SL5) represents an example of an RNA structural element, repeatedly occurring in coronaviruses. It contains a conserved, repetitive...

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المؤلف الرئيسي:	Klara R. Mertinkus (19936612) (author)
مؤلفون آخرون:	Andreas Oxenfarth (10498412) (author), Christian Richter (147050) (author), Anna Wacker (1788904) (author), Carlos P. Mata (3829603) (author), Jose Maria Carazo (19936615) (author), Andreas Schlundt (224586) (author), Harald Schwalbe (24749) (author)
منشور في:	2024
الموضوعات:	Biophysics Biochemistry Medicine Molecular Biology Biotechnology Evolutionary Biology Infectious Diseases Plant Biology Computational Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified solution nmr methods repetitive fold within remote parts located located immediately upstream 5 ′ region b start codon rna structural element length 5_sl5 structures structural differences loop element fifth element unique ability resolution models repeatedly occurring pair stability loop substructures individual base herein report detailed characterization conformational heterogeneity apical loops
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Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5′-Untranslated Region of SARS-CoV‑2

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