L-2HG and LDHC guarded centromere morphology in diakinesis cells.

<p>(A) Experimental Design (Created with Biorender). This experiment aimed to study the effect of 2HG on compacting oxamate-decompacted diakinesis centromeres. Diakinesis cells were isolated from two groups: mice injected once with oxamate (1.3 g/kg) and sacrificed after 24 hours (Ox) and mice...

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Auteur principal:	Nina Mayorek (241888) (author)
Autres auteurs:	Miriam Schlossberg (21696644) (author), Yousef Mansour (21696647) (author), Nir Pillar (5249612) (author), Ilan Stein (131429) (author), Fatima Mushasha (21696650) (author), Guy Baziza Paz (21696653) (author), Eleonora Medvedev (21696656) (author), Zakhariya Manevitch (21696659) (author), Julia Menzel (12879920) (author), Elina Aizenshtein (21696662) (author), Boris Sarvin (8232306) (author), Nikita Sarvin (21696665) (author), Erwin Goldberg (2868524) (author), Bryan A. Niedenberger (21696668) (author), Christopher B. Geyer (13840432) (author), Tomer Shlomi (22999) (author), Michael Klutstein (22329) (author), Eli Pikarsky (103960) (author)
Publié:	2025
Sujets:	Cell Biology Genetics Molecular Biology Developmental Biology Biological Sciences not elsewhere classified spindle assembly checkpoint satellite rna expression sac ), suggesting producing functional spermatozoa histone methylation changes including chromocenter clustering 2hg ), yet regulates centromere condensation hydroxyglutarate regulates centromere chromocenter condensation centromere dysfunction vivo results synaptonemal complex localizing along heterochromatin conformation epigenetic modifications diplotene stages acute depletion
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L-2HG and LDHC guarded centromere morphology in diakinesis cells.

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