Image 3_Investigation of early axonal phenotypes in an iPSC-derived ALS cellular model using a microfluidic device.tif

Image 3_Investigation of early axonal phenotypes in an iPSC-derived ALS cellular model using a microfluidic device.tif

Introduction<p>Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease caused by the loss of upper and lower motor neurons. Mutations in the FUS/TLS gene have been reported as the second most common mutation in Japanese patients with familial ALS. In recent years, lower...

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Auteur principal: Asako Otomo (251531) (author)
Autres auteurs: Keiko Nishijima (21776255) (author), Yuta Murakami (2178398) (author), Mitsuru Ishikawa (606461) (author), Haruka Yudahira (21776258) (author), Kento Shimakura (21776261) (author), Hideyuki Okano (47690) (author), Masashi Aoki (35088) (author), Hiroshi Kimura (3849) (author), Shinji Hadano (251529) (author)
Publié: 2025
Sujets:
Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)
amyotrophic lateral sclerosis (ALS)
iPSCs
microfluidic device
FUS/TLS
lower motor neurons
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