Chloroquine boosted apoptosis induced by clozapine.
<p>MCF-7 cells were treated with 50 μM of clozapine for 72 h, with or without chloroquine, followed by measuring (A) cell proliferation via MTT assay, (B) intracellular ROS content by H<sub>2</sub>DCFDA uptake assay, and (C) apoptotic percentages by flow cytometry. (D) Total protei...
-д хадгалсан:
| Үндсэн зохиолч: | |
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| Бусад зохиолчид: | , , , , |
| Хэвлэсэн: |
2025
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| Нөхцлүүд: | |
| Шошгууд: |
Шошго нэмэх
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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| Тойм: | <p>MCF-7 cells were treated with 50 μM of clozapine for 72 h, with or without chloroquine, followed by measuring (A) cell proliferation via MTT assay, (B) intracellular ROS content by H<sub>2</sub>DCFDA uptake assay, and (C) apoptotic percentages by flow cytometry. (D) Total protein lysates from each treatment of clozapine and/or chloroquine were collected to assess cleaved caspase 9 levels after 3 days of incubation. Data were plotted as mean ± standard deviation (S.D.). P value below 0.05 was denoted with the asterisks, where * indicates < 0.05; ** means < 0.01.</p> |
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