Survival data of BALB/c mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.

Survival data of BALB/c mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.

<p>Survival data of BALB/c mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.</p>

Պահպանված է:

Մատենագիտական մանրամասներ
Հիմնական հեղինակ:	Jianhua Liao (1393228) (author)
Այլ հեղինակներ:	Jun Cheng (194158) (author), Baoqing Liu (1508821) (author), Yuzhi Shao (22683349) (author), Chunyan Meng (5993228) (author)
Հրապարակվել է:	2025
Խորագրեր:	Medicine Microbiology Cell Biology Biotechnology Evolutionary Biology Ecology Science Policy Infectious Diseases Virology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified therapeutic strategies aimed novel therapeutic approaches murine infection model div >< p defense mechanisms employed conserved gene encoding compromising membrane stability affect biofilm formation staphylococcus aureus </ reduced bacterial burden improved host survival maintaining mrsa ’ oxidative stress resistance yqhg </ withstand host reduced motility oxidative stress increasing resistance stress adaptation potential target periplasmic protein mrsa virulence mrsa pathogenesis key determinant infected organs increased sensitivity imposed stresses growing prevalence findings highlight existing antibiotics critical need attenuates virulence
Ցուցիչներ:	Ավելացրեք ցուցիչ Չկան պիտակներ, Եղեք առաջինը, ով նշում է այս գրառումը!

Նմանատիպ նյութեր

Kidney bacterial burden in mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Heart bacterial burden in mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Crystal violet quantification of biofilm formation in MRSA wild-type, ΔyqhG, and complemented strains.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Spleen bacterial burden in mice infected with MRSA wild-type, ΔyqhG, and complemented strains.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Liver bacterial burden in mice infected with MRSA wild-type, ΔyqhG, and complemented strains.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Optical density measurements of MRSA wild-type, Δ<i>yqhG</i>, and complemented strains during <i>in vitro</i> growth.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Amount of PSMs (μg/1mL culture) in MRSA wild-type, ΔyqhG, and complemented strains.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Surface motility of the <i>yqhG</i> mutant.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Membrane integrity in the <i>yqhG</i> mutant.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Quantification of cell-associated PSMs in wild-type, Δ<i>yqhG</i>, and complemented strains. Cell-associated PSMs were extracted from bacterial pellets using 6 M guanidine hydrochloride and quantified by reversed-phase HPLC. The Δ<i>yqhG</i> mutant exhibited a significant reduction in surface-bound PSMs compared with the wild-type strain, whereas complementation restored PSM levels to near wild-type values. Data represent mean ± s.e.m. from three independent experiments. Statistical analysis was performed using one-way ANOVA; *<i>P</i> < 0.05, ns, not significant.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Oxidative stress resistance of the <i>yqhG</i> mutant.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

YqhG is required for systemic virulence but not for <i>in vitro</i> growth.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Biofilm formation in MRSA strains.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Primers Used in This Study.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Bacterial Strains and Plasmids Used in This Study.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Viable CFU counts following hydrogen peroxide exposure.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Colony diameter measurements from soft agar motility assays.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

SYTOX Green fluorescence measurements for membrane permeability assessment.
‌: Jianhua Liao (1393228)
Հրապարակվել է: (2025)

Table 1_Hard to jump: host shifts appear unlikely in a T4-like phage evolved in the lab.xlsx
‌: Yu Ning (588573)
Հրապարակվել է: (2025)

Supplementary file 1_Hard to jump: host shifts appear unlikely in a T4-like phage evolved in the lab.docx
‌: Yu Ning (588573)
Հրապարակվել է: (2025)

Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
‌: Wei-hua Yuan (22683169)
Հրապարակվել է: (2025)

Protocatechuic Acid alleviates D-gal-induced renal senescence and injury in mice by regulating taurine metabolism
‌: Songhao Tian (22609826)
Հրապարակվել է: (2025)

Table 1_Melatonin mitigates cadmium-induced oxidative damage and modulates polysaccharide biosynthesis in Bletilla striata.xlsx
‌: Deqiong Niu (19691873)
Հրապարակվել է: (2025)

Data Sheet 1_Melatonin mitigates cadmium-induced oxidative damage and modulates polysaccharide biosynthesis in Bletilla striata.docx
‌: Deqiong Niu (19691873)
Հրապարակվել է: (2025)

Effects of <i>T. gondii</i> infection on rat gut microbiota diversity.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Untargeted serum metabolomics analysis before and after <i>T. gondii</i> infection.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Functional analysis of the intestinal microbial community following <i>T. gondii</i> infection.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Composition of intestinal microbial communities in the large intestine of rats before and after <i>T. gondii</i> infection.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Composition of intestinal microbial communities in the small intestine of rats before and after <i>T. gondii</i> infection.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Differential metabolite results, listing metabolites with significant changes across treatment groups, including fold changes, and <i>p</i>-values.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Correlation network between intestinal bacterial species and differential serum metabolites.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

KEGG pathway enrichment analysis of differential serum metabolites.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Spearman correlation analysis between gut microbial taxa and circulating metabolites, detailing correlation coefficients, significance values, and taxon–metabolite pairings indicative of microbiome–host metabolic interactions.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Orthogonal partial least squares-discriminant analysis (OPLS-DA) of serum metabolomics data.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Quality control assessment of serum metabolomics data.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Heatmap of enriched KEGG pathways across samples, illustrating variations in pathway abundance.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

Graphical abstract.
‌: Ji-Xin Zhao (22056386)
Հրապարակվել է: (2025)

The U sequence method.
‌: Pierre Angelvy (22683450)
Հրապարակվել է: (2025)

Provisional study schedule of MUSIBOT.
‌: Pierre Angelvy (22683450)
Հրապարակվել է: (2025)

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