Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docx

Introduction<p>The gut microbiota plays a pivotal role in regulating the host's physiological functions and behavior. The coevolutionary relationship between the host and its gut microbiota facilitates adaptation to specific ecological niches. As obligate bamboo feeders, giant pandas (Ail...

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Egile nagusia: Yanshan Zhou (14131359) (author)
Beste egile batzuk: Dunwu Qi (510967) (author), Chao Chen (195669) (author), Wenlei Bi (14131368) (author), Xiang Yu (70326) (author), Jiabin Liu (58465) (author), Guanwei Lan (14131365) (author), Rong Hou (149003) (author), Zusheng Li (14131362) (author), Rui Ma (239028) (author)
Argitaratua: 2025
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author Yanshan Zhou (14131359)
author2 Dunwu Qi (510967)
Chao Chen (195669)
Wenlei Bi (14131368)
Xiang Yu (70326)
Jiabin Liu (58465)
Guanwei Lan (14131365)
Rong Hou (149003)
Zusheng Li (14131362)
Rui Ma (239028)
author2_role author
author
author
author
author
author
author
author
author
author_facet Yanshan Zhou (14131359)
Dunwu Qi (510967)
Chao Chen (195669)
Wenlei Bi (14131368)
Xiang Yu (70326)
Jiabin Liu (58465)
Guanwei Lan (14131365)
Rong Hou (149003)
Zusheng Li (14131362)
Rui Ma (239028)
author_role author
dc.creator.none.fl_str_mv Yanshan Zhou (14131359)
Dunwu Qi (510967)
Chao Chen (195669)
Wenlei Bi (14131368)
Xiang Yu (70326)
Jiabin Liu (58465)
Guanwei Lan (14131365)
Rong Hou (149003)
Zusheng Li (14131362)
Rui Ma (239028)
dc.date.none.fl_str_mv 2025-11-25T13:37:06Z
dc.identifier.none.fl_str_mv 10.3389/fmicb.2025.1698108.s001
dc.relation.none.fl_str_mv https://figshare.com/articles/dataset/Supplementary_file_1_Divergent_gut_microbial_metabolism_supports_niche_partitioning_in_giant_and_red_pandas_docx/30709850
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Microbiology
giant pandas
red pandas
gut microbiota
metagenome
niche differentiation
dc.title.none.fl_str_mv Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docx
dc.type.none.fl_str_mv Dataset
info:eu-repo/semantics/publishedVersion
dataset
description Introduction<p>The gut microbiota plays a pivotal role in regulating the host's physiological functions and behavior. The coevolutionary relationship between the host and its gut microbiota facilitates adaptation to specific ecological niches. As obligate bamboo feeders, giant pandas (Ailuropoda melanoleuca) and red pandas (Ailurus styani) exhibit distinct feeding preferences: the former primarily consumes bamboo stems and leaves, while the latter feeds mainly on bamboo leaves. This study aims to elucidate how these species adapt metabolically to different parts of bamboo via gut microbial activity.</p>Methods<p>We employed 16S rRNA gene sequencing to analyze the structure and function of fecal microbial communities in giant pandas (GP) and red pandas (RP).</p>Results<p>Significant differences in gut microbiota composition were observed between the GP and RP groups. Eight core bacterial taxa constituted over 99.97% of the total microbial composition, with the RP group exhibiting higher species richness but lower overall diversity. At the phylum level, Proteobacteria, Bacteroidetes, Actinobacteria, Acidobacteria, and Flavobacteria were significantly enriched in the GP group, whereas Firmicutes dominated in the RP group. At the genus level, Sphingomonas, Methylobacterium, Cryomonas, and Terriglobus were more abundant in the GP group, while Streptococcus and Rhizobium were enriched in the RP group. Functional metabolic analysis indicated that lipid and amino acid metabolism pathways were significantly enriched in the GP group, whereas nucleotide and carbohydrate metabolism pathways were prominent in the RP group. Further analysis revealed that Sphingomonas and Methylobacterium in the GP group positively regulated amino acid and lipid metabolism, while Streptococcus in the RP group enhanced nucleotide and carbohydrate metabolism.</p>Discussion<p>These findings suggest that the distinct metabolic pathways of the gut microbiota in giant and red pandas have evolved in concert with their dietary strategies, energy acquisition modes, and ecological niche differentiation, forming a highly coordinated adaptive system.</p>
eu_rights_str_mv openAccess
id Manara_28abdd9a235f6d66c870f6eb8ef3f1a8
identifier_str_mv 10.3389/fmicb.2025.1698108.s001
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30709850
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docxYanshan Zhou (14131359)Dunwu Qi (510967)Chao Chen (195669)Wenlei Bi (14131368)Xiang Yu (70326)Jiabin Liu (58465)Guanwei Lan (14131365)Rong Hou (149003)Zusheng Li (14131362)Rui Ma (239028)Microbiologygiant pandasred pandasgut microbiotametagenomeniche differentiationIntroduction<p>The gut microbiota plays a pivotal role in regulating the host's physiological functions and behavior. The coevolutionary relationship between the host and its gut microbiota facilitates adaptation to specific ecological niches. As obligate bamboo feeders, giant pandas (Ailuropoda melanoleuca) and red pandas (Ailurus styani) exhibit distinct feeding preferences: the former primarily consumes bamboo stems and leaves, while the latter feeds mainly on bamboo leaves. This study aims to elucidate how these species adapt metabolically to different parts of bamboo via gut microbial activity.</p>Methods<p>We employed 16S rRNA gene sequencing to analyze the structure and function of fecal microbial communities in giant pandas (GP) and red pandas (RP).</p>Results<p>Significant differences in gut microbiota composition were observed between the GP and RP groups. Eight core bacterial taxa constituted over 99.97% of the total microbial composition, with the RP group exhibiting higher species richness but lower overall diversity. At the phylum level, Proteobacteria, Bacteroidetes, Actinobacteria, Acidobacteria, and Flavobacteria were significantly enriched in the GP group, whereas Firmicutes dominated in the RP group. At the genus level, Sphingomonas, Methylobacterium, Cryomonas, and Terriglobus were more abundant in the GP group, while Streptococcus and Rhizobium were enriched in the RP group. Functional metabolic analysis indicated that lipid and amino acid metabolism pathways were significantly enriched in the GP group, whereas nucleotide and carbohydrate metabolism pathways were prominent in the RP group. Further analysis revealed that Sphingomonas and Methylobacterium in the GP group positively regulated amino acid and lipid metabolism, while Streptococcus in the RP group enhanced nucleotide and carbohydrate metabolism.</p>Discussion<p>These findings suggest that the distinct metabolic pathways of the gut microbiota in giant and red pandas have evolved in concert with their dietary strategies, energy acquisition modes, and ecological niche differentiation, forming a highly coordinated adaptive system.</p>2025-11-25T13:37:06ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.3389/fmicb.2025.1698108.s001https://figshare.com/articles/dataset/Supplementary_file_1_Divergent_gut_microbial_metabolism_supports_niche_partitioning_in_giant_and_red_pandas_docx/30709850CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307098502025-11-25T13:37:06Z
spellingShingle Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docx
Yanshan Zhou (14131359)
Microbiology
giant pandas
red pandas
gut microbiota
metagenome
niche differentiation
status_str publishedVersion
title Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docx
title_full Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docx
title_fullStr Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docx
title_full_unstemmed Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docx
title_short Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docx
title_sort Supplementary file 1_Divergent gut microbial metabolism supports niche partitioning in giant and red pandas.docx
topic Microbiology
giant pandas
red pandas
gut microbiota
metagenome
niche differentiation