RNG2 spans between the APR and the conoid, forming 22 tethers.

RNG2 spans between the APR and the conoid, forming 22 tethers.

<p><b>(A)</b> Illustration of endogenous tagging of RNG2, including three epitope tags and a minimal auxin inducible (mAID) motif. The estimation of the protein length corresponding to the distance coverage of the central part of the protein in linear conformation. <b>(B)<...

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Detaylı Bibliyografya
Yazar:	Romuald Haase (22339777) (author)
Diğer Yazarlar:	Bingjian Ren (22676577) (author), Albert Tell i Puig (22676580) (author), Alessandro Bonavoglia (19415718) (author), Jean-Baptiste Marq (375239) (author), Rémy Visentin (22676583) (author), Nicolas Dos Santos Pacheco (22676586) (author), Bohumil Maco (383443) (author), Ricardo Mondragón-Flores (10737057) (author), Oscar Vadas (2416228) (author), Dominique Soldati-Favre (79026) (author)
Baskı/Yayın Bilgisi:	2025
Konular:	Biophysics Biochemistry Microbiology Cell Biology Physiology Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Physical Sciences not elsewhere classified toxoplasma gondii </ remains apically anchored heterologous expression systems div >< p apical polar ring biochemical analysis revealed proper conoid anchorage ensures conoid functionality less parasites revealed host cell invasion enable parasite motility controlling parasite motility although rng2 depletion intact conoid organelle organelle traverses intact protein conditional depletion biochemical properties detached conoid gliding motility unstable protein undergoes extrusion two structures strong candidate striking detachment still unclear rng2 tethers rng2 led rng2 emerges rhoptries follow resilient bridge protein localized plasma membrane pivotal protein likely facilitate large coiled immunoelectron microscopy functional activity enabling rng2 electron tomography dependent extrusion critical role concatenated assemblies comprehensive mutagenesis coil domains calcium waves
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Benzer Materyaller

Model RNG2 as a molecular tether for conoid apical anchorage.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

Phenotypic consequences of the conoid detachment.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

RNG2 depletion leads to conoid detachment from the apical pole of the parasite.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

Detachment of the conoid in absence of RNG2 impairs parasite motility and invasion, additional phenotyping of the RNG2-mAID strain.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

RNG2 is functional only as intact, full-length protein.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

Investigation of RNG2 subdomain functions.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

Biochemical investigation of wild-type and processed RNG2.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

<i>Toxoplasma gondii</i> tachyzoite cell organization.
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Baskı/Yayın Bilgisi: (2025)

Reconstruction of the Fig 4E panel III.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

Reconstruction of the Fig 4E panel II.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

Reconstruction of the Fig 4E panel I.
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Baskı/Yayın Bilgisi: (2025)

Source Numerical Data of this study.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

Additional information on antibodies and primers used in this study.
Yazar:: Romuald Haase (22339777)
Baskı/Yayın Bilgisi: (2025)

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Additional information on the cryo-electron tomography performed on RNG2-mAID strain.
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Baskı/Yayın Bilgisi: (2025)

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Baskı/Yayın Bilgisi: (2025)

Multiple epitopes-tagging across RNG2.
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Baskı/Yayın Bilgisi: (2025)

Additional information of the RNG2 purification from insect cells.
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Baskı/Yayın Bilgisi: (2025)

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Baskı/Yayın Bilgisi: (2025)

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Baskı/Yayın Bilgisi: (2025)

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