Strain-specific analysis of RVA RNA levels in extraintestinal tissues.

<p>Six-day-old germ-free pigs were orally inoculated with 1 × 10⁶ FFU of each rotavirus. At the indicated post-inoculation time points, animals were euthanized, and tissues (lungs, salivary glands, liver, blood, and spleen) were collected. <b>(A)</b> RT-qPCR RVA RNA detection frequ...

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Autore principale:	Sergei A. Raev (15350287) (author)
Altri autori:	Maryssa K. Kick (17183901) (author), Maria Chellis (22683628) (author), Linda J. Saif (6626666) (author), Talita P. Resende (3916268) (author), Anastasia N. Vlasova (6626663) (author)
Pubblicazione:	2025
Soggetti:	Biophysics Biochemistry Microbiology Ecology Infectious Diseases Space Science Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified increased sialic acid host characteristics regulate first experimental evidence findings may provide current global dominance rva rna detection multiple extraintestinal organs div >< p rva strains replicated related rva strains porcine osu g5p facilitating viral dissemination efficient extraintestinal spread rva receptor diversity rva extraintestinal spread examined extraintestinal tissues gut </ p extraintestinal tissues extraintestinal spread extraintestinal tissue extraintestinal sites also examined vivo </ vitro </ different tissues well understood respiratory lesions remarkably robust potential role pigs infected moderate titers microscopic lesions intestinal tissue inoculated germ highest titers highest frequency higher rate free pigs determine whether better understand
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Strain-specific analysis of RVA RNA levels in extraintestinal tissues.

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