Frequencies of p24 + cells across Fiebig stages.
<p>(A) Frequencies of p24 + cells in CD4 T cells for each individual according to the stage of ART initiation at UD, UD + 5 and UD + x. Open circles represent limit of detection (LOD). (B) Percentages of HIV-infected cells expressing the p24 protein following stimulation for each individual ac...
Gardado en:
| Autor Principal: | |
|---|---|
| Outros autores: | , , , , , , , |
| Publicado: |
2025
|
| Subjects: | |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|
| _version_ | 1849927626391552000 |
|---|---|
| author | Tine Struyve (22683295) |
| author2 | Marion Pardons (6407921) Jozefien De Clercq (17737815) Liesbet Termote (22683298) Laurens Lambrechts (10532207) Ytse Noppe (22683301) Mathias Lichterfeld (57148) Sofie Rutsaert (10667718) Linos Vandekerckhove (105574) |
| author2_role | author author author author author author author author |
| author_facet | Tine Struyve (22683295) Marion Pardons (6407921) Jozefien De Clercq (17737815) Liesbet Termote (22683298) Laurens Lambrechts (10532207) Ytse Noppe (22683301) Mathias Lichterfeld (57148) Sofie Rutsaert (10667718) Linos Vandekerckhove (105574) |
| author_role | author |
| dc.creator.none.fl_str_mv | Tine Struyve (22683295) Marion Pardons (6407921) Jozefien De Clercq (17737815) Liesbet Termote (22683298) Laurens Lambrechts (10532207) Ytse Noppe (22683301) Mathias Lichterfeld (57148) Sofie Rutsaert (10667718) Linos Vandekerckhove (105574) |
| dc.date.none.fl_str_mv | 2025-11-25T18:40:28Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.ppat.1013702.s006 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Frequencies_of_p24_cells_across_Fiebig_stages_/30714889 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biochemistry Medicine Neuroscience Biotechnology Evolutionary Biology Ecology Cancer Infectious Diseases Plant Biology Virology Computational Biology phorbol myristate acetate integration selection mechanisms xlink "> persistence small reservoir sizes treatment initiation timing clonal expansion contributes art ), irrespective individuals treated shortly reservoir persistence early reservoir persistence clonal expansion started treatment pma ), art initiation viral reservoir treated individuals inducible reservoir individuals treated 1 reservoir suggesting post proviruses integrated progressively enriched one year major barrier longitudinal analysis heterochromatin regions five years chronic cohorts cell compartment antiretroviral therapy already detected |
| dc.title.none.fl_str_mv | Frequencies of p24 + cells across Fiebig stages. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>(A) Frequencies of p24 + cells in CD4 T cells for each individual according to the stage of ART initiation at UD, UD + 5 and UD + x. Open circles represent limit of detection (LOD). (B) Percentages of HIV-infected cells expressing the p24 protein following stimulation for each individual according to the stage of ART initiation at UD, UD + 5 and UD + x. (C) Paired longitudinal frequencies of p24 + cells in CD4 T cells for the acute cohort (p = 0.6875). Open circles represent the limit of detection (LOD). (D) Percentages of HIV-infected cells expressing the p24 protein following stimulation for paired samples of the acute cohort (p = 0.3750). (A-B) Two-tailed Mann-Whitney tests and (C-D) Wilcoxon tests were performed. Only significant p-values (p < 0.05) are represented on the graphs.</p> <p>(TIF)</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_2a5785f5b6dc598dedb89f48d1f6578a |
| identifier_str_mv | 10.1371/journal.ppat.1013702.s006 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30714889 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Frequencies of p24 + cells across Fiebig stages.Tine Struyve (22683295)Marion Pardons (6407921)Jozefien De Clercq (17737815)Liesbet Termote (22683298)Laurens Lambrechts (10532207)Ytse Noppe (22683301)Mathias Lichterfeld (57148)Sofie Rutsaert (10667718)Linos Vandekerckhove (105574)BiochemistryMedicineNeuroscienceBiotechnologyEvolutionary BiologyEcologyCancerInfectious DiseasesPlant BiologyVirologyComputational Biologyphorbol myristate acetateintegration selection mechanismsxlink "> persistencesmall reservoir sizestreatment initiation timingclonal expansion contributesart ), irrespectiveindividuals treated shortlyreservoir persistence earlyreservoir persistenceclonal expansionstarted treatmentpma ),art initiationviral reservoirtreated individualsinducible reservoirindividuals treated1 reservoirsuggesting postproviruses integratedprogressively enrichedone yearmajor barrierlongitudinal analysisheterochromatin regionsfive yearschronic cohortscell compartmentantiretroviral therapyalready detected<p>(A) Frequencies of p24 + cells in CD4 T cells for each individual according to the stage of ART initiation at UD, UD + 5 and UD + x. Open circles represent limit of detection (LOD). (B) Percentages of HIV-infected cells expressing the p24 protein following stimulation for each individual according to the stage of ART initiation at UD, UD + 5 and UD + x. (C) Paired longitudinal frequencies of p24 + cells in CD4 T cells for the acute cohort (p = 0.6875). Open circles represent the limit of detection (LOD). (D) Percentages of HIV-infected cells expressing the p24 protein following stimulation for paired samples of the acute cohort (p = 0.3750). (A-B) Two-tailed Mann-Whitney tests and (C-D) Wilcoxon tests were performed. Only significant p-values (p < 0.05) are represented on the graphs.</p> <p>(TIF)</p>2025-11-25T18:40:28ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.ppat.1013702.s006https://figshare.com/articles/figure/Frequencies_of_p24_cells_across_Fiebig_stages_/30714889CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307148892025-11-25T18:40:28Z |
| spellingShingle | Frequencies of p24 + cells across Fiebig stages. Tine Struyve (22683295) Biochemistry Medicine Neuroscience Biotechnology Evolutionary Biology Ecology Cancer Infectious Diseases Plant Biology Virology Computational Biology phorbol myristate acetate integration selection mechanisms xlink "> persistence small reservoir sizes treatment initiation timing clonal expansion contributes art ), irrespective individuals treated shortly reservoir persistence early reservoir persistence clonal expansion started treatment pma ), art initiation viral reservoir treated individuals inducible reservoir individuals treated 1 reservoir suggesting post proviruses integrated progressively enriched one year major barrier longitudinal analysis heterochromatin regions five years chronic cohorts cell compartment antiretroviral therapy already detected |
| status_str | publishedVersion |
| title | Frequencies of p24 + cells across Fiebig stages. |
| title_full | Frequencies of p24 + cells across Fiebig stages. |
| title_fullStr | Frequencies of p24 + cells across Fiebig stages. |
| title_full_unstemmed | Frequencies of p24 + cells across Fiebig stages. |
| title_short | Frequencies of p24 + cells across Fiebig stages. |
| title_sort | Frequencies of p24 + cells across Fiebig stages. |
| topic | Biochemistry Medicine Neuroscience Biotechnology Evolutionary Biology Ecology Cancer Infectious Diseases Plant Biology Virology Computational Biology phorbol myristate acetate integration selection mechanisms xlink "> persistence small reservoir sizes treatment initiation timing clonal expansion contributes art ), irrespective individuals treated shortly reservoir persistence early reservoir persistence clonal expansion started treatment pma ), art initiation viral reservoir treated individuals inducible reservoir individuals treated 1 reservoir suggesting post proviruses integrated progressively enriched one year major barrier longitudinal analysis heterochromatin regions five years chronic cohorts cell compartment antiretroviral therapy already detected |