Transformer Decoder Learns from a Pretrained Protein Language Model to Generate Ligands with High Affinity

The drug discovery process can be significantly accelerated by using deep learning methods to suggest molecules with druglike features and, more importantly, that are good candidates to bind specific proteins of interest. We present a novel deep learning generative model, Prot2Drug, that learns to g...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Teresa Maria Creanza (11420282) (author)
مؤلفون آخرون: Domenico Alberga (1503991) (author), Cosimo Patruno (20627228) (author), Giuseppe Felice Mangiatordi (804889) (author), Nicola Ancona (28781) (author)
منشور في: 2025
الموضوعات:
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