Spearman correlation coefficient (rs) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD).

Spearman correlation coefficient (rs) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammati...

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Bibliographic Details
Main Author:	Maria C. Jugan (18928389) (author)
Other Authors:	Gabrielle A. Rands (22676472) (author), Joerg M. Steiner (6887384) (author), Natalia Cernicchiaro (783181) (author), Matthew C. Tanner (22676475) (author), Lillian M. Novotny (22676478) (author)
Published:	2025
Subjects:	Medicine Microbiology Cell Biology Physiology Biotechnology Ecology Immunology Cancer Science Policy Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified muscle condition score linear regression models fisher exact test evaluate possible associations body condition score gastrointestinal barrier function inflammatory biomarkers based stage c disease gastrointestinal clinical signs lps ), interleukins including 25 dogs e ., il div >< p stage b2 disease gastrointestinal bacterial translocation group 2 ), mmvd stage severity gastrointestinal signs bacterial translocation b2 disease gastrointestinal microbiome inflammatory markers disease progresses cardiovascular disease group 2 group 1 xlink "> untreated mmvd twenty percent therapeutic targets study indicates study aimed spearman ’ six client serum lps serum lipopolysaccharide serum il potential relationship positively correlated owned dogs mmvd severity mmvd ). maybe even groups 1 findings warrant fecal scores enrolled prospectively echocardiographic diagnosis compare proportions compare lps
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