Figure 4 from Extracellular Vesicle Secretion by Leukemia Cells <i>In Vivo</i> Promotes CLL Progression by Hampering Antitumor T-cell Responses

Figure 4 from Extracellular Vesicle Secretion by Leukemia Cells <i>In Vivo</i> Promotes CLL Progression by Hampering Antitumor T-cell Responses

<p>LME-sEVs impact CD8<sup>+</sup> T-cell transcriptome, proteome, and metabolome. <b>A,</b> Volcano plot showing DEG identified by RNA-seq from CD8<sup>+</sup> T cells treated for 48 hours with LME- (<i>n</i> = 4) or HCME-sEVs (<i>n</i&...

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Main Author: Ernesto Gargiulo (15134961) (author)
Other Authors: Elodie Viry (15134964) (author), Pablo Elías Morande (15134967) (author), Anne Largeot (15134970) (author), Susanne Gonder (15134973) (author), Feng Xian (15134976) (author), Nikolaos Ioannou (15134979) (author), Mohaned Benzarti (15134982) (author), Felix Bruno Kleine Borgmann (15134985) (author), Michel Mittelbronn (15134988) (author), Gunnar Dittmar (15134991) (author), Petr V. Nazarov (15134994) (author), Johannes Meiser (15134997) (author), Basile Stamatopoulos (15135000) (author), Alan G. Ramsay (15021857) (author), Etienne Moussay (15135003) (author), Jérôme Paggetti (15135006) (author)
Published: 2025
Subjects:
Cancer
Tumor Biology
Immuno-oncology
Methods and Technology
Hematological Cancers
Leukemias
Lymphomas
Immunology
T cell exhaustion
Tumor resistance to immune response
Preclinical Models
Animal models of cancer
Tumor Microenvironment
Immune cells and the microenvironment
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