Figure 2 from Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models

Figure 2 from Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models

<p>ART558 treatment leads to increased residual IR-induced DNA damage foci. <b>A,</b> γH2AX and 53BP1 foci in HCT116 and H460 cells treated with 3 μmol/L ART558 and 4 Gy IR, assessed at the indicated times points after IR. <b>B,</b> Representative images from irradiated...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autor: Gonzalo Rodriguez-Berriguete (15056057) (author)
Další autoři: Marco Ranzani (15056060) (author), Remko Prevo (15056063) (author), Rathi Puliyadi (15056066) (author), Nicole Machado (15056069) (author), Hannah R. Bolland (15056072) (author), Val Millar (15056075) (author), Daniel Ebner (15056078) (author), Marie Boursier (15056081) (author), Aurora Cerutti (15056084) (author), Alessandro Cicconi (15056087) (author), Alessandro Galbiati (15056090) (author), Diego Grande (15056093) (author), Vera Grinkevich (15056096) (author), Jayesh B. Majithiya (15056099) (author), Desiree Piscitello (15056102) (author), Eeson Rajendra (15056105) (author), Martin L. Stockley (15056108) (author), Simon J. Boulton (15056111) (author), Ester M. Hammond (15056114) (author), Robert A. Heald (15056117) (author), Graeme C.M. Smith (15056120) (author), Helen M.R. Robinson (15056123) (author), Geoff S. Higgins (15056126) (author)
Vydáno: 2025
Témata:
Cancer
Molecular and Cellular Biology
Therapeutic Research and Development
DNA Damage and Repair
DNA repair
Radiation Oncology
Molecular targets of radiation response
Small Molecule Agents
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Podobné jednotky

Podobné jednotky