Figure 4 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
<p>Single-gene expression changes of genes in common between baseline and surgery in the different cohorts. <b>A,</b> Scatterplot of differentially expressed genes between baseline and surgery measured by log<sub>2</sub> FC among the entire short-term and long-term AI c...
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2025
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| Summary: | <p>Single-gene expression changes of genes in common between baseline and surgery in the different cohorts. <b>A,</b> Scatterplot of differentially expressed genes between baseline and surgery measured by log<sub>2</sub> FC among the entire short-term and long-term AI cohorts. <b>B,</b> Scatterplot of differentially expressed genes between baseline and surgery measured by log<sub>2</sub> FC among Luminal B–treated tumors only in the short-term and long-term AI cohorts <b>C,</b> Boxplot showing the intersections of common genes differentially expressed between baseline and surgery among different combinations of subgroups of sample patients within the POETIC and NeoAI cohorts: all treated patients in POETIC, only treated with Luminal A in POETIC, only treated with Luminal B in POETIC, all patients in NeoAI, only Luminal A in NeoAI, only Luminal B patients in NeoAI, only controls in POETIC. FDR, false discovery rate; log<sub>2</sub> FC, log<sub>2</sub> fold change.</p> |
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