Image 3_A comprehensive longitudinal analysis of the cellular immune response specific to the spike protein in healthcare workers vaccinated against SARS-CoV-2– ORCHESTRA Project.pdf

Image 3_A comprehensive longitudinal analysis of the cellular immune response specific to the spike protein in healthcare workers vaccinated against SARS-CoV-2– ORCHESTRA Project.pdf

Introduction<p>The long-term dynamics of T-cell immunity following SARS-CoV-2 vaccination, essential for durable protection, remain incompletely understood. This study, therefore, aimed to investigate the kinetics and persistence of spike-specific T-cell responses in vaccinated healthcare work...

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Main Author: Stefano Ugel (7402733) (author)
Other Authors: Akshita Gupta (9861964) (author), Gianluca Spiteri (13881092) (author), Pierpaolo Marchetti (3574394) (author), Francesco De Sanctis (8497395) (author), Shari Wouters (22679114) (author), Angelina Konnova (14292068) (author), Maria Grazia Lourdes Monaco (13881095) (author), Angela Carta (384367) (author), Maria Diletta Pezzani (22679117) (author), Filippo Liviero (11175000) (author), Sofia Pavanello (550275) (author), Marco dell’Omo (8872523) (author), Eleonóra Fabiánová (162234) (author), Jana Bérešová (13881107) (author), Francesca Larese Filon (11527932) (author), Marcella Mauro (11527929) (author), Giuseppe Verlato (412001) (author), Vincenzo Bronte (234424) (author), Samir Kumar-Singh (305527) (author), Stefano Porru (384360) (author), Orchestra WP5 and WP6 Working Groups (22679141) (author)
Published: 2025
Subjects:
Genetic Immunology
SARS-CoV-2 infection (COVID-19)
mRNA vaccine against SARS-CoV-2
post-vaccination immunity
anti-spike T-cell response
cytotoxic T cells (CTLs)
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