Schematic overview of cyanogenesis in <i>Chamberlinius hualienensis</i> and cyanohydrin biosynthesis in millipedes, insects, and plants.

Schematic overview of cyanogenesis in <i>Chamberlinius hualienensis</i> and cyanohydrin biosynthesis in millipedes, insects, and plants.

<p>(A) <i>C. hualienensis</i> and a schematic view of cyanogenesis. Paranota of the millipede house defensive glands and consist of reservoir and reaction chamber. (<i>R</i>)-Mandelonitrile (MAN) stored in the reservoir is admitted to the reaction chamber, converted by...

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मुख्य लेखक:	Takuya Yamaguchi (4543105) (author)
अन्य लेखक:	Yasuhisa Asano (727606) (author)
प्रकाशित:	2025
विषय:	Biochemistry Evolutionary Biology Ecology Plant Biology Virology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified subsequently converting aldoxime natural defensive chemicals indicating sequential duplication catalyse aldoxime dehydration div >< p cyanogenic millipedes evolved chamberlinius hualienensis </ hualienensis </ r </ typically lineage related enzymes plant lineages plant kingdoms paralogous genes millipedes demonstrates mechanisms underlying hydroxynitrile lyase hydrogen cyanide giving rise enzymes independently dependent monooxygenase deeper understanding cytochrome p450 complete set coding genes biological characterisation >)- mandelonitrile
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समान संसाधन

Distribution of cyanogenesis-related enzymes in millipedes.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Assembly and annotation statistics of <i>Chamberlinius hualienensis</i> genome.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Body weight and accumulation of (<i>R</i>)-mandelonitrile in <i>Chamberlinius hualienensis.</i>
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Characteristics of flavin-dependent monooxygenases (FMOs) from <i>Chamberlinius hualienensis.</i>
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Identification of phenylacetaldoxime (PAOx)-producing flavin dependent monooxygenase from <i>Chamberlinius hualienensis.</i>
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Overview of the processing pipeline used for the assembly of the <i>Chamberlinius hualienensis genome</i> (see materials and methods for detail).
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Amino acid sequence alignment (A) and amino acid sequence identity (B) of CHUA_008368 (CYP4GL4) from <i>Chamberlinius hualienensis</i>, Hho_020879 from <i>Helicorthomorpha holstii.</i>
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Amino acid sequence alignment (A) and amino acid sequence identity (B) of CHUA_003298 (ChuaMOxS) from <i>Chamberlinius hualienensis</i>, Hho_019011 from <i>Helicorthomorpha holstii</i>, and Nno_033811 from <i>Niponia nodulosa.</i>
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

<i>C. hualienensis</i> genome annotation.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Amino acid sequence alignment (A) and and amino acid sequence identity (B) of CHUA_014123 (CYP30008A2) from <i>Chamberlinius hualienensis</i> and its orthorogous proteins, Hho_011653 from <i>Helicorthomorpha holstii</i> and Nno_033394 from <i>Niponia nodulosa.</i>
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Identification of (<i>R</i>)-mandelonitrile biosynthetic enzymes from <i>C. hualienensis.</i>
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

TE contents of millipede and centipede.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

GenomeScope plot of the 21-mer content within the <i>C. hualienensis</i> genome.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Detection of aromatic amino acids-derived aldoximes after the culture of <i>Escherichia coli</i> harboring millipede aldoxime synthase (MOxS, CHUA_003298).
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Amino acid sequence alignment (A) and sequence identity matrix (B) of <i>Chamberliniensis hualienensis</i> flavin-dependent monooxygenases.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Correlations of genome sizes and TE contents among millipedes and centipedes.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Three dimensional structures of hydroxynitrile lyase (HNL) from millipede, plant, and microorganism.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Phylogenetic tree of millipede HNLs, their paralogous proteins, and lipocalins from animals (arthropoda and chordata), plants, and bacteria.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Comparison of phenylacetonitrile (PAN) metabolizing activity of <i>Saccharomyces cerevisiae</i> ChCR11 and INVSc1 expressing <i>CYP3201B1.</i>
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Gene cluster and characterisation of <i>ChuaHNL</i> and its paralogues.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

TMM normalized read counts of (<i>R</i>)-mandelonitrile biosynthetic genes.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Heterologous production of ChuaHNL and its paralogous proteins in <i>Pichia pastoris.</i>
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Substrate saturation curves for CHUA_005138 (ChuaHNL), CHUA_005137, and CHUA_005136 with (<i>R,S</i>)-mandelonitrile (mandelonitrile cleavage reaction) (A) or benzaldehyde ((<i>R</i>)-mandelonitrile synthetic reaction) (B).
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

(<i>R</i>)-mandelonitrile synthetic reaction catalyzed by CHUA_005138 (ChuaHNL), CHUA_005137, and CHUA_005136.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Purification of N-terminal His-tagged CHUA_005136 from 1.5 L of <i>Pichia pastoris</i> culture supernatant.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Purification of N-terminal His-tagged CHUA_005137 from 1.5 L of <i>Pichia pastoris</i> culture supernatant.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Purification of N-terminal His-tagged ChuaHNL (CHUA_005138) from 1.5 L of <i>Pichia pastoris</i> culture supernatant.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Characterization of CYP4GL4 (CHUA_008368) and CYP30008A2 (CHUA_014123) catalyzing dehydration of (<i>E/Z</i>)-phenylacetaldoxime (PAOx) into phenylacetonitrile.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Formation of phenylacetonitrile (PAN) from (<i>E/Z</i>)-phenylacetaldoxime by yeast harboring CHUA_008368 (CYP4GL4) and CHUA_014123 (CYP30008A2).
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Numerical data underlying Figs 3, 4E, S4, S8, S10, S12, S13,
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

TMM normalized read counts of flavin-dependent monooxygenases (FMOs).
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

RNA-seq for gene expression analysis.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

RNA-seq for gene annotation.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Shotgun sequencing summary statistics (PacBio).
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Shotgun sequencing summary statistics (Illumina).
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Flavin-dependent monooxygenases in myriapods and other species.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Substrate specificity of CYP4GL4 (CHUA_008368) and CYP30008A2 (CHUA_014123) toward aromatic aldoximes.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Phylogenetic tree of cytochrome P450s.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Amino acid sequence alignment of ChuaHNL and its paralogous proteins.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

Amino acid sequence identity matrix of ChuaHNL and its paralogous proteins.
द्वारा: Takuya Yamaguchi (4543105)
प्रकाशित: (2025)

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