Figure 3 from Prostate Cancer Progression Modeling Provides Insight into Dynamic Molecular Changes Associated with Progressive Disease States
<p>Enrichment analysis of T-stage and summary GS mapped onto four identified progression paths. <b>A,</b> T-stage. Tumor samples with T-stages 3 and 4 were plotted on the top (red), and those with T-stages 1 and 2 plotted at the bottom (black). <b>B,</b> Summary GS. Tum...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , |
| منشور في: |
2024
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| الموضوعات: | |
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إضافة وسم
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| الملخص: | <p>Enrichment analysis of T-stage and summary GS mapped onto four identified progression paths. <b>A,</b> T-stage. Tumor samples with T-stages 3 and 4 were plotted on the top (red), and those with T-stages 1 and 2 plotted at the bottom (black). <b>B,</b> Summary GS. Tumor samples with summary GS ≥ 4 + 3 were plotted on the top (red), and those with summary GS ≤ 3 + 4 plotted at the bottom (black). The <i>x</i>-axis represents the progression distances of tumor samples along a path, and <i>P</i> values were computed through 10,000 permutation tests. A negative enrichment score (defined as the maximum deviation of a running sum statistic from zero) indicates that T-stage ≥ 3 or GS ≥ 4 + 3 tumors were enriched at the end of a progression path, and a broken line indicates the location of the enrichment score on the progression path.</p> |
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