Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment

<p>The relationship between NPM1 dependency and cell line metastatic propensity, determined from genome-wide CRISPR-Cas9 screens (https://depmap.org/portal/interactive). A score of zero indicates that a gene is not essential. Common essential genes have a median score of -1. A lower score indi...

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Prif Awdur: Konjeti R. Sekhar (15400345) (author)
Awduron Eraill: Michael L. Freeman (15400348) (author)
Cyhoeddwyd: 2025
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author Konjeti R. Sekhar (15400345)
author2 Michael L. Freeman (15400348)
author2_role author
author_facet Konjeti R. Sekhar (15400345)
Michael L. Freeman (15400348)
author_role author
dc.creator.none.fl_str_mv Konjeti R. Sekhar (15400345)
Michael L. Freeman (15400348)
dc.date.none.fl_str_mv 2025-11-24T23:01:13Z
dc.identifier.none.fl_str_mv 10.1158/0008-5472.30699922
dc.relation.none.fl_str_mv https://figshare.com/articles/dataset/Supplementary_Table_S2_from_Nucleophosmin_Plays_a_Role_in_Repairing_DNA_Damage_and_Is_a_Target_for_Cancer_Treatment/30699922
dc.rights.none.fl_str_mv CC BY
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cancer
Molecular and Cellular Biology
Therapeutic Research and Development
DNA Damage and Repair
Genomic instability
Small Molecule Agents
dc.title.none.fl_str_mv Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
dc.type.none.fl_str_mv Dataset
info:eu-repo/semantics/publishedVersion
dataset
description <p>The relationship between NPM1 dependency and cell line metastatic propensity, determined from genome-wide CRISPR-Cas9 screens (https://depmap.org/portal/interactive). A score of zero indicates that a gene is not essential. Common essential genes have a median score of -1. A lower score indicates that a gene is more likely to be dependent in a given cell line.</p>
eu_rights_str_mv openAccess
id Manara_351571ec4687ae39419f517daabca3be
identifier_str_mv 10.1158/0008-5472.30699922
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30699922
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY
spelling Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer TreatmentKonjeti R. Sekhar (15400345)Michael L. Freeman (15400348)CancerMolecular and Cellular BiologyTherapeutic Research and DevelopmentDNA Damage and RepairGenomic instabilitySmall Molecule Agents<p>The relationship between NPM1 dependency and cell line metastatic propensity, determined from genome-wide CRISPR-Cas9 screens (https://depmap.org/portal/interactive). A score of zero indicates that a gene is not essential. Common essential genes have a median score of -1. A lower score indicates that a gene is more likely to be dependent in a given cell line.</p>2025-11-24T23:01:13ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.1158/0008-5472.30699922https://figshare.com/articles/dataset/Supplementary_Table_S2_from_Nucleophosmin_Plays_a_Role_in_Repairing_DNA_Damage_and_Is_a_Target_for_Cancer_Treatment/30699922CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/306999222025-11-24T23:01:13Z
spellingShingle Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
Konjeti R. Sekhar (15400345)
Cancer
Molecular and Cellular Biology
Therapeutic Research and Development
DNA Damage and Repair
Genomic instability
Small Molecule Agents
status_str publishedVersion
title Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
title_full Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
title_fullStr Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
title_full_unstemmed Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
title_short Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
title_sort Supplementary Table S2 from Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
topic Cancer
Molecular and Cellular Biology
Therapeutic Research and Development
DNA Damage and Repair
Genomic instability
Small Molecule Agents