Chromocenters and centromeres in round spermatids are also affected by L-2HG manipulation.

Chromocenters and centromeres in round spermatids are also affected by L-2HG manipulation.

<p>(A) RS cells were isolated using FACS-sorter and incubated for 24 hours with 24 mM oxamate. Relative concentrations of 2HG were quantified using LC-MS. (B-C) RS cells were isolated from mice injected once with oxamate (1.3 g/kg) and sacrificed after 24 hours (Ox) and from mice injected with...

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Bibliografiske detaljer
Hovedforfatter: Nina Mayorek (241888) (author)
Andre forfattere: Miriam Schlossberg (21696644) (author), Yousef Mansour (21696647) (author), Nir Pillar (5249612) (author), Ilan Stein (131429) (author), Fatima Mushasha (21696650) (author), Guy Baziza Paz (21696653) (author), Eleonora Medvedev (21696656) (author), Zakhariya Manevitch (21696659) (author), Julia Menzel (12879920) (author), Elina Aizenshtein (21696662) (author), Boris Sarvin (8232306) (author), Nikita Sarvin (21696665) (author), Erwin Goldberg (2868524) (author), Bryan A. Niedenberger (21696668) (author), Christopher B. Geyer (13840432) (author), Tomer Shlomi (22999) (author), Michael Klutstein (22329) (author), Eli Pikarsky (103960) (author)
Udgivet: 2025
Fag:
Cell Biology
Genetics
Molecular Biology
Developmental Biology
Biological Sciences not elsewhere classified
spindle assembly checkpoint
satellite rna expression
sac ), suggesting
producing functional spermatozoa
histone methylation changes
including chromocenter clustering
2hg ), yet
regulates centromere condensation
hydroxyglutarate regulates centromere
chromocenter condensation
centromere dysfunction
vivo results
synaptonemal complex
localizing along
heterochromatin conformation
epigenetic modifications
diplotene stages
acute depletion
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