Chromocenters and centromeres in round spermatids are also affected by L-2HG manipulation.

<p>(A) RS cells were isolated using FACS-sorter and incubated for 24 hours with 24 mM oxamate. Relative concentrations of 2HG were quantified using LC-MS. (B-C) RS cells were isolated from mice injected once with oxamate (1.3 g/kg) and sacrificed after 24 hours (Ox) and from mice injected with...

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Autor Principal:	Nina Mayorek (241888) (author)
Outros autores:	Miriam Schlossberg (21696644) (author), Yousef Mansour (21696647) (author), Nir Pillar (5249612) (author), Ilan Stein (131429) (author), Fatima Mushasha (21696650) (author), Guy Baziza Paz (21696653) (author), Eleonora Medvedev (21696656) (author), Zakhariya Manevitch (21696659) (author), Julia Menzel (12879920) (author), Elina Aizenshtein (21696662) (author), Boris Sarvin (8232306) (author), Nikita Sarvin (21696665) (author), Erwin Goldberg (2868524) (author), Bryan A. Niedenberger (21696668) (author), Christopher B. Geyer (13840432) (author), Tomer Shlomi (22999) (author), Michael Klutstein (22329) (author), Eli Pikarsky (103960) (author)
Publicado:	2025
Subjects:	Cell Biology Genetics Molecular Biology Developmental Biology Biological Sciences not elsewhere classified spindle assembly checkpoint satellite rna expression sac ), suggesting producing functional spermatozoa histone methylation changes including chromocenter clustering 2hg ), yet regulates centromere condensation hydroxyglutarate regulates centromere chromocenter condensation centromere dysfunction vivo results synaptonemal complex localizing along heterochromatin conformation epigenetic modifications diplotene stages acute depletion
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Chromocenters and centromeres in round spermatids are also affected by L-2HG manipulation.

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