Sirt1 mRNA expression data and clinical outcomes in patients receiving sodium valproate: training and validation cohorts.
<p dir="ltr">epilepsyThis dataset contains complete Sirt1 gene expression data (ΔCt, ΔΔCt, and relative expression values) from 303 subjects, including a training set (n = 235) and a validation set (n = 68). Each subject was measured at three time points: baseline, 2 weeks, and 8 wee...
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2025
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| Summary: | <p dir="ltr">epilepsyThis dataset contains complete Sirt1 gene expression data (ΔCt, ΔΔCt, and relative expression values) from 303 subjects, including a training set (n = 235) and a validation set (n = 68). Each subject was measured at three time points: baseline, 2 weeks, and 8 weeks after treatment with sodium valproate.</p><p><br></p><p dir="ltr">The dataset includes:</p><p dir="ltr">1. Ct values for Sirt1 and β-actin (reference gene)</p><p dir="ltr">2. ΔCt and ΔΔCt calculations</p><p dir="ltr">3. Relative expression (2^-ΔΔCt) for each time point</p><p dir="ltr">4. Clinical outcome (presence or absence of postoperative epileptic seizures, POE)</p><p><br></p><p dir="ltr">All data are complete without missing values, and β-actin Ct values are stable (22.0–22.9), confirming reference gene stability.</p><p><br></p><p dir="ltr">This dataset supports the reproducibility of the analyses presented in [Full manuscript title], which investigated the predictive value of Sirt1 expression dynamics for treatment outcomes.</p><p><br></p><p dir="ltr">File format: Excel (.xlsx)</p><p dir="ltr">License: CC BY 4.0</p> |
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