Changes in neural selectivity caused by PV cell activation reflect behavioral performance in easy but not difficult discriminations.

Changes in neural selectivity caused by PV cell activation reflect behavioral performance in easy but not difficult discriminations.

<p><b>A)</b> Optogenetic stimulation timings for entire and early window conditions aligned to stimulus onset (STIM ON) or offset (STIM OFF) (top), schematic of optogenetic method combined with 2-photon imaging (middle), schematic of laser activating only ChrimsonR-expressing PV ce...

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Bibliographic Details
Main Author: Lilia Kukovska (22683586) (author)
Other Authors: Katharina A. Wilmes (22683589) (author), Natsumi Y. Homma (22683592) (author), Claudia Clopath (324706) (author), Jasper Poort (22683595) (author)
Published: 2025
Subjects:
Biochemistry
Neuroscience
Developmental Biology
Science Policy
Mental Health
Biological Sciences not elsewhere classified
xlink "> inhibition
three major factors
strong competitive interactions
photon imaging showed
balanced cortical activity
primary visual cortex
sustained v1 activity
combined optogenetic activation
v1 cells captured
moderate pv activation
moderate activation
visual discriminations
expressing cells
nonlinear activation
dependent activation
activation strength
task difficulty
stimulus onset
perceptual discrimination
difficult discriminations
delineates conditions
circuit model
behavioral effects
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