Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung Cancer

<p>Supplementary Figure 19. (A) Objective response rate, (B) progression-free survival, and (C) overall survival to PD-(L)1 immune checkpoint blockade monotherapy among patients with ATMMUT NSCLC, according to KEAP1 mutation. (D) Objective response rate, (E) progression-free survival, and (F)...

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Главный автор: Biagio Ricciuti (14951247) (author)
Другие авторы: Arielle Elkrief (15055750) (author), Joao Alessi (15561455) (author), Xinan Wang (15561458) (author), Yvonne Li (15561461) (author), Hersh Gupta (15561464) (author), Daniel M. Muldoon (15561467) (author), Arrien A. Bertram (14954848) (author), Federica Pecci (15561470) (author), Giuseppe Lamberti (15024714) (author), Alessandro Di Federico (15561473) (author), Adriana Barrichello (15561476) (author), Victor R. Vaz (15561479) (author), Malini Gandhi (15561482) (author), Elinton Lee (15561485) (author), Geoffrey I. Shapiro (14961801) (author), Hyesun Park (15561488) (author), Mizuki Nishino (15561491) (author), James Lindsay (15032271) (author), Kristen D. Felt (15561494) (author), Bijaya Sharma (15561497) (author), Andrew D. Cherniack (14959412) (author), Scott Rodig (15561500) (author), Daniel R. Gomez (15561503) (author), Narek Shaverdian (15561506) (author), Mehrdad Rakaee (15561509) (author), Chaitanya Bandlamudi (15047205) (author), Marc Ladanyi (15050661) (author), Pasi A. Janne (15561512) (author), Adam J. Schoenfeld (15022025) (author), Lynette M. Sholl (15032729) (author), Mark M. Awad (14961722) (author), Michael L. Cheng (15561515) (author)
Опубликовано: 2025
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_version_ 1849927632032890880
author Biagio Ricciuti (14951247)
author2 Arielle Elkrief (15055750)
Joao Alessi (15561455)
Xinan Wang (15561458)
Yvonne Li (15561461)
Hersh Gupta (15561464)
Daniel M. Muldoon (15561467)
Arrien A. Bertram (14954848)
Federica Pecci (15561470)
Giuseppe Lamberti (15024714)
Alessandro Di Federico (15561473)
Adriana Barrichello (15561476)
Victor R. Vaz (15561479)
Malini Gandhi (15561482)
Elinton Lee (15561485)
Geoffrey I. Shapiro (14961801)
Hyesun Park (15561488)
Mizuki Nishino (15561491)
James Lindsay (15032271)
Kristen D. Felt (15561494)
Bijaya Sharma (15561497)
Andrew D. Cherniack (14959412)
Scott Rodig (15561500)
Daniel R. Gomez (15561503)
Narek Shaverdian (15561506)
Mehrdad Rakaee (15561509)
Chaitanya Bandlamudi (15047205)
Marc Ladanyi (15050661)
Pasi A. Janne (15561512)
Adam J. Schoenfeld (15022025)
Lynette M. Sholl (15032729)
Mark M. Awad (14961722)
Michael L. Cheng (15561515)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Biagio Ricciuti (14951247)
Arielle Elkrief (15055750)
Joao Alessi (15561455)
Xinan Wang (15561458)
Yvonne Li (15561461)
Hersh Gupta (15561464)
Daniel M. Muldoon (15561467)
Arrien A. Bertram (14954848)
Federica Pecci (15561470)
Giuseppe Lamberti (15024714)
Alessandro Di Federico (15561473)
Adriana Barrichello (15561476)
Victor R. Vaz (15561479)
Malini Gandhi (15561482)
Elinton Lee (15561485)
Geoffrey I. Shapiro (14961801)
Hyesun Park (15561488)
Mizuki Nishino (15561491)
James Lindsay (15032271)
Kristen D. Felt (15561494)
Bijaya Sharma (15561497)
Andrew D. Cherniack (14959412)
Scott Rodig (15561500)
Daniel R. Gomez (15561503)
Narek Shaverdian (15561506)
Mehrdad Rakaee (15561509)
Chaitanya Bandlamudi (15047205)
Marc Ladanyi (15050661)
Pasi A. Janne (15561512)
Adam J. Schoenfeld (15022025)
Lynette M. Sholl (15032729)
Mark M. Awad (14961722)
Michael L. Cheng (15561515)
author_role author
dc.creator.none.fl_str_mv Biagio Ricciuti (14951247)
Arielle Elkrief (15055750)
Joao Alessi (15561455)
Xinan Wang (15561458)
Yvonne Li (15561461)
Hersh Gupta (15561464)
Daniel M. Muldoon (15561467)
Arrien A. Bertram (14954848)
Federica Pecci (15561470)
Giuseppe Lamberti (15024714)
Alessandro Di Federico (15561473)
Adriana Barrichello (15561476)
Victor R. Vaz (15561479)
Malini Gandhi (15561482)
Elinton Lee (15561485)
Geoffrey I. Shapiro (14961801)
Hyesun Park (15561488)
Mizuki Nishino (15561491)
James Lindsay (15032271)
Kristen D. Felt (15561494)
Bijaya Sharma (15561497)
Andrew D. Cherniack (14959412)
Scott Rodig (15561500)
Daniel R. Gomez (15561503)
Narek Shaverdian (15561506)
Mehrdad Rakaee (15561509)
Chaitanya Bandlamudi (15047205)
Marc Ladanyi (15050661)
Pasi A. Janne (15561512)
Adam J. Schoenfeld (15022025)
Lynette M. Sholl (15032729)
Mark M. Awad (14961722)
Michael L. Cheng (15561515)
dc.date.none.fl_str_mv 2025-11-25T13:28:55Z
dc.identifier.none.fl_str_mv 10.1158/1078-0432.30709318
dc.relation.none.fl_str_mv https://figshare.com/articles/figure/Supplementary_Figure_19_from_Clinicopathologic_Genomic_and_Immunophenotypic_Landscape_of_i_ATM_i_Mutations_in_Non_Small_Cell_Lung_Cancer/30709318
dc.rights.none.fl_str_mv CC BY
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cancer
Molecular and Cellular Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Clinical Research and Trials
Biomarkers
Genetic biomarkers
DNA Damage and Repair
DNA repair
Lung Cancer
Precision Medicine
Translational Research
dc.title.none.fl_str_mv Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung Cancer
dc.type.none.fl_str_mv Image
Figure
info:eu-repo/semantics/publishedVersion
image
description <p>Supplementary Figure 19. (A) Objective response rate, (B) progression-free survival, and (C) overall survival to PD-(L)1 immune checkpoint blockade monotherapy among patients with ATMMUT NSCLC, according to KEAP1 mutation. (D) Objective response rate, (E) progression-free survival, and (F) overall survival to PD-(L)1 immune checkpoint blockade in combination with platinum doublet chemotherapy among patients with ATMMUT NSCLC, according to KEAP1 mutation status</p>
eu_rights_str_mv openAccess
id Manara_3812402e3171b1a640a60cde8432f127
identifier_str_mv 10.1158/1078-0432.30709318
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30709318
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY
spelling Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung CancerBiagio Ricciuti (14951247)Arielle Elkrief (15055750)Joao Alessi (15561455)Xinan Wang (15561458)Yvonne Li (15561461)Hersh Gupta (15561464)Daniel M. Muldoon (15561467)Arrien A. Bertram (14954848)Federica Pecci (15561470)Giuseppe Lamberti (15024714)Alessandro Di Federico (15561473)Adriana Barrichello (15561476)Victor R. Vaz (15561479)Malini Gandhi (15561482)Elinton Lee (15561485)Geoffrey I. Shapiro (14961801)Hyesun Park (15561488)Mizuki Nishino (15561491)James Lindsay (15032271)Kristen D. Felt (15561494)Bijaya Sharma (15561497)Andrew D. Cherniack (14959412)Scott Rodig (15561500)Daniel R. Gomez (15561503)Narek Shaverdian (15561506)Mehrdad Rakaee (15561509)Chaitanya Bandlamudi (15047205)Marc Ladanyi (15050661)Pasi A. Janne (15561512)Adam J. Schoenfeld (15022025)Lynette M. Sholl (15032729)Mark M. Awad (14961722)Michael L. Cheng (15561515)CancerMolecular and Cellular BiologyCancer Detection and DiagnosisTherapeutic Research and DevelopmentClinical Research and TrialsBiomarkersGenetic biomarkersDNA Damage and RepairDNA repairLung CancerPrecision MedicineTranslational Research<p>Supplementary Figure 19. (A) Objective response rate, (B) progression-free survival, and (C) overall survival to PD-(L)1 immune checkpoint blockade monotherapy among patients with ATMMUT NSCLC, according to KEAP1 mutation. (D) Objective response rate, (E) progression-free survival, and (F) overall survival to PD-(L)1 immune checkpoint blockade in combination with platinum doublet chemotherapy among patients with ATMMUT NSCLC, according to KEAP1 mutation status</p>2025-11-25T13:28:55ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/1078-0432.30709318https://figshare.com/articles/figure/Supplementary_Figure_19_from_Clinicopathologic_Genomic_and_Immunophenotypic_Landscape_of_i_ATM_i_Mutations_in_Non_Small_Cell_Lung_Cancer/30709318CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/307093182025-11-25T13:28:55Z
spellingShingle Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung Cancer
Biagio Ricciuti (14951247)
Cancer
Molecular and Cellular Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Clinical Research and Trials
Biomarkers
Genetic biomarkers
DNA Damage and Repair
DNA repair
Lung Cancer
Precision Medicine
Translational Research
status_str publishedVersion
title Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung Cancer
title_full Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung Cancer
title_fullStr Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung Cancer
title_full_unstemmed Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung Cancer
title_short Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung Cancer
title_sort Supplementary Figure 19 from Clinicopathologic, Genomic, and Immunophenotypic Landscape of <i>ATM</i> Mutations in Non–Small Cell Lung Cancer
topic Cancer
Molecular and Cellular Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Clinical Research and Trials
Biomarkers
Genetic biomarkers
DNA Damage and Repair
DNA repair
Lung Cancer
Precision Medicine
Translational Research