Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers

<p>Module scores expression changes in the POETIC cohort. <b>A</b>, Barplots showing the significant module scores expression changes between baseline and after 2 weeks of AI in the POETIC dataset for all samples, for Luminal B samples only (<b>B</b>) and for controls (...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Milana A. Bergamino (15038015) (author)
مؤلفون آخرون: Gabriele Morani (15038018) (author), Joel Parker (15038021) (author), Eugene F. Schuster (9726535) (author), Mariana F. Leal (15038024) (author), Elena López-Knowles (15038027) (author), Holly Tovey (9360536) (author), Judith M. Bliss (8827107) (author), John F.R. Robertson (15025368) (author), Ian E. Smith (1545553) (author), Mitch Dowsett (645) (author), Maggie C.U. Cheang (14946768) (author)
منشور في: 2025
الموضوعات:
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author Milana A. Bergamino (15038015)
author2 Gabriele Morani (15038018)
Joel Parker (15038021)
Eugene F. Schuster (9726535)
Mariana F. Leal (15038024)
Elena López-Knowles (15038027)
Holly Tovey (9360536)
Judith M. Bliss (8827107)
John F.R. Robertson (15025368)
Ian E. Smith (1545553)
Mitch Dowsett (645)
Maggie C.U. Cheang (14946768)
author2_role author
author
author
author
author
author
author
author
author
author
author
author_facet Milana A. Bergamino (15038015)
Gabriele Morani (15038018)
Joel Parker (15038021)
Eugene F. Schuster (9726535)
Mariana F. Leal (15038024)
Elena López-Knowles (15038027)
Holly Tovey (9360536)
Judith M. Bliss (8827107)
John F.R. Robertson (15025368)
Ian E. Smith (1545553)
Mitch Dowsett (645)
Maggie C.U. Cheang (14946768)
author_role author
dc.creator.none.fl_str_mv Milana A. Bergamino (15038015)
Gabriele Morani (15038018)
Joel Parker (15038021)
Eugene F. Schuster (9726535)
Mariana F. Leal (15038024)
Elena López-Knowles (15038027)
Holly Tovey (9360536)
Judith M. Bliss (8827107)
John F.R. Robertson (15025368)
Ian E. Smith (1545553)
Mitch Dowsett (645)
Maggie C.U. Cheang (14946768)
dc.date.none.fl_str_mv 2025-11-25T12:05:29Z
dc.identifier.none.fl_str_mv 10.1158/1078-0432.30705377
dc.relation.none.fl_str_mv https://figshare.com/articles/figure/Figure_2_from_Impact_of_Duration_of_Neoadjuvant_Aromatase_Inhibitors_on_Molecular_Expression_Profiles_in_Estrogen_Receptor_positive_Breast_Cancers/30705377
dc.rights.none.fl_str_mv CC BY
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cancer
Tumor Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Biomarkers
Genetic biomarkers
Breast Cancer
Drug Resistance
Novel mechanisms
Endocrinology
Translational Research
dc.title.none.fl_str_mv Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
dc.type.none.fl_str_mv Image
Figure
info:eu-repo/semantics/publishedVersion
image
description <p>Module scores expression changes in the POETIC cohort. <b>A</b>, Barplots showing the significant module scores expression changes between baseline and after 2 weeks of AI in the POETIC dataset for all samples, for Luminal B samples only (<b>B</b>) and for controls (<b>C</b>). The <i>x</i>-axis shows the log<sub>2</sub>FC and the <i>y</i>-axis shows the significant module scores that changed. Bars are colored by the degree of significance of the <i>P</i> value by paired <i>t</i> test. FDR; false discovery rate; log<sub>2</sub> FC, log<sub>2</sub> fold change.</p>
eu_rights_str_mv openAccess
id Manara_39acb68b4a3ee9e82afa6897868beee0
identifier_str_mv 10.1158/1078-0432.30705377
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30705377
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY
spelling Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast CancersMilana A. Bergamino (15038015)Gabriele Morani (15038018)Joel Parker (15038021)Eugene F. Schuster (9726535)Mariana F. Leal (15038024)Elena López-Knowles (15038027)Holly Tovey (9360536)Judith M. Bliss (8827107)John F.R. Robertson (15025368)Ian E. Smith (1545553)Mitch Dowsett (645)Maggie C.U. Cheang (14946768)CancerTumor BiologyCancer Detection and DiagnosisTherapeutic Research and DevelopmentBiomarkersGenetic biomarkersBreast CancerDrug ResistanceNovel mechanismsEndocrinologyTranslational Research<p>Module scores expression changes in the POETIC cohort. <b>A</b>, Barplots showing the significant module scores expression changes between baseline and after 2 weeks of AI in the POETIC dataset for all samples, for Luminal B samples only (<b>B</b>) and for controls (<b>C</b>). The <i>x</i>-axis shows the log<sub>2</sub>FC and the <i>y</i>-axis shows the significant module scores that changed. Bars are colored by the degree of significance of the <i>P</i> value by paired <i>t</i> test. FDR; false discovery rate; log<sub>2</sub> FC, log<sub>2</sub> fold change.</p>2025-11-25T12:05:29ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/1078-0432.30705377https://figshare.com/articles/figure/Figure_2_from_Impact_of_Duration_of_Neoadjuvant_Aromatase_Inhibitors_on_Molecular_Expression_Profiles_in_Estrogen_Receptor_positive_Breast_Cancers/30705377CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/307053772025-11-25T12:05:29Z
spellingShingle Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
Milana A. Bergamino (15038015)
Cancer
Tumor Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Biomarkers
Genetic biomarkers
Breast Cancer
Drug Resistance
Novel mechanisms
Endocrinology
Translational Research
status_str publishedVersion
title Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
title_full Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
title_fullStr Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
title_full_unstemmed Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
title_short Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
title_sort Figure 2 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
topic Cancer
Tumor Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Biomarkers
Genetic biomarkers
Breast Cancer
Drug Resistance
Novel mechanisms
Endocrinology
Translational Research