Supplementary Figure 1 from <i>ALK</i> Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma

Supplementary Figure 1 from <i>ALK</i> Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma

<p>Supplementary Figure 1: Characterization of the novel LRRFIP1-ALK fusion (case ALK.223) A. Visualization of the read coverage at the fusion sites in ALK and LRRFIP1 genes using Integrative Genomic Viewer.B. Pile-up plot generated by SvABA using whole-genome sequencing data shows the breakpo...

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Main Author: Anne-Florence Blandin (15056366) (author)
Other Authors: Ross Giglio (15056369) (author), Maya Srikanth Graham (15056372) (author), Guadalupe Garcia (15056375) (author), Seth Malinowski (15056378) (author), Jared K. Woods (15056381) (author), Shakti Ramkissoon (15056384) (author), Lori Ramkissoon (15056387) (author), Frank Dubois (15056390) (author), Kathleen Schoolcraft (15056393) (author), Jessica Tsai (15056396) (author), Dayle Wang (15056399) (author), Robert Jones (15056402) (author), Jayne Vogelzang (15056405) (author), Kristine Pelton (15056408) (author), Sarah Becker (15056411) (author), Fiona Watkinson (15056414) (author), Claire Sinai (15056417) (author), Elizabeth F. Cohen (15056420) (author), Matthew A. Booker (15056423) (author), Michael Y. Tolstorukov (15056426) (author), Veerle Haemels (15056429) (author), Liliana Goumnerova (15056432) (author), Karen Wright (15056435) (author), Mark Kieran (15056438) (author), Katie Fehnel (15056441) (author), David Reardon (15056444) (author), Arnault Tauziede-Espariat (15056447) (author), Rishi Lulla (15056450) (author), Benjamin Carcamo (15056453) (author), Stanley Chaleff (15056456) (author), Alain Charest (15056459) (author), Frederik De Smet (14957559) (author), Azra H. Ligon (15056462) (author), Adrian Dubuc (15056465) (author), Melanie Pages (15056468) (author), Pascale Varlet (15056471) (author), Patrick Y. Wen (15056474) (author), Brian M. Alexander (15019467) (author), Susan Chi (15056477) (author), Sanda Alexandrescu (9122099) (author), Ralf Kittler (14864988) (author), Robert Bachoo (15056480) (author), Pratiti Bandopadhayay (15056483) (author), Rameen Beroukhim (15056486) (author), Keith L. Ligon (14958845) (author)
Published: 2025
Subjects:
Cancer
Cancer Biology
Molecular and Cellular Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Methods and Technology
Biomarkers
Cell Signaling
Receptors
CNS Cancers
Gliomas, Glioblastomas
Drug Targets
Protein kinase & phosphatase drug targets
Oncogenes & Tumor Suppressors
Oncogenes
Pediatric Cancers
Preclinical Models
Xenograft models
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