Reliable expression of ChR2-EYFP and ChrimsonR-tdTomato in PV cells.

Reliable expression of ChR2-EYFP and ChrimsonR-tdTomato in PV cells.

<p><b>A)</b> Example confocal fluorescence imaging region in primary visual cortex of PV-cre::Ai32 mice showing expression of ChR2-EYFP (left) at cell membrane of PV cells (right). <b>B)</b> Percentage of PV cells with expression of ChR2-EYFP at the cell membrane in thr...

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Main Author: Lilia Kukovska (22683586) (author)
Other Authors: Katharina A. Wilmes (22683589) (author), Natsumi Y. Homma (22683592) (author), Claudia Clopath (324706) (author), Jasper Poort (22683595) (author)
Published: 2025
Subjects:
Biochemistry
Neuroscience
Developmental Biology
Science Policy
Mental Health
Biological Sciences not elsewhere classified
xlink "> inhibition
three major factors
strong competitive interactions
photon imaging showed
balanced cortical activity
primary visual cortex
sustained v1 activity
combined optogenetic activation
v1 cells captured
moderate pv activation
moderate activation
visual discriminations
expressing cells
nonlinear activation
dependent activation
activation strength
task difficulty
stimulus onset
perceptual discrimination
difficult discriminations
delineates conditions
circuit model
behavioral effects
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