Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study
<p>Endoscopic nasopharyngectomy represents a significant intervention for recurrent nasopharyngeal carcinoma (NPC). Various surgical techniques, including transnasal and transoral approaches, are employed. However, the impact of these procedures on nasal airflow dynamics is not well understood...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , , |
| منشور في: |
2024
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| الموضوعات: | |
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| _version_ | 1852026378637017088 |
|---|---|
| author | Dong Dong (23216) |
| author2 | Hui Li (32376) Mu Qin (122222) Jiasong Tian (19743669) Xinjie Qiao (19743672) Haojie Hu (18793634) Yitong Song (17481129) Chao Wang (146527) Yulin Zhao (273330) |
| author2_role | author author author author author author author author |
| author_facet | Dong Dong (23216) Hui Li (32376) Mu Qin (122222) Jiasong Tian (19743669) Xinjie Qiao (19743672) Haojie Hu (18793634) Yitong Song (17481129) Chao Wang (146527) Yulin Zhao (273330) |
| author_role | author |
| dc.creator.none.fl_str_mv | Dong Dong (23216) Hui Li (32376) Mu Qin (122222) Jiasong Tian (19743669) Xinjie Qiao (19743672) Haojie Hu (18793634) Yitong Song (17481129) Chao Wang (146527) Yulin Zhao (273330) |
| dc.date.none.fl_str_mv | 2024-09-26T07:00:03Z |
| dc.identifier.none.fl_str_mv | 10.6084/m9.figshare.27108474.v1 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/dataset/Alterations_in_nasal_airflow_and_air_conditioning_after_endoscopic_nasopharyngectomy_for_recurrent_nasopharyngeal_carcinoma_a_pilot_computational_fluid_dynamics_study/27108474 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Medicine Physiology Cancer Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Chemical Sciences not elsewhere classified Nasal airflow endoscopic nasopharyngectomy recurrent nasopharyngeal carcinoma computational fluid dynamics air conditioning |
| dc.title.none.fl_str_mv | Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study |
| dc.type.none.fl_str_mv | Dataset info:eu-repo/semantics/publishedVersion dataset |
| description | <p>Endoscopic nasopharyngectomy represents a significant intervention for recurrent nasopharyngeal carcinoma (NPC). Various surgical techniques, including transnasal and transoral approaches, are employed. However, the impact of these procedures on nasal airflow dynamics is not well understood. This computational fluid dynamics (CFD) study aimed to investigate alterations in nasal airflow and air conditioning following endoscopic nasopharyngectomy. A 55-year-old male patient with recurrent NPC was selected, whose CT data were utilized for image reconstruction. A preoperative model and two postoperative models, including the transnasal and transoral approach models, were established. The airflow patterns and various CFD parameters were analyzed. In the postoperative models, the high-speed airflow went along the soft palate and into the nasopharyngeal outlet, and there was the low-speed turbulence in the expanded nasopharyngeal cavity. Compared to the preoperative model, the postoperative models exhibited reductions in surface-to-volume ratio, nasal resistance, airflow velocity and proportion of high wall shear stress regions in nasopharynx. The changing trends of nasopharyngeal air temperature and humidity in the preoperative and transoral models were consistent. The heating and humidification efficiency decreased in the transnasal model compared to the transoral model. The endoscopic nasopharyngectomy for recurrent NPC affects the nasal airflow and warming and humidification function. The transoral approach has less influence on aerodynamics of the upper airway compared to the transnasal approach. From a CFD perspective, the endoscopic nasopharyngectomy does not increase the risk of postoperative complications, including the empty nose syndrome and the carotid blowout syndrome.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_3c53e0de4e8e032ce79c19390c843f0e |
| identifier_str_mv | 10.6084/m9.figshare.27108474.v1 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/27108474 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics studyDong Dong (23216)Hui Li (32376)Mu Qin (122222)Jiasong Tian (19743669)Xinjie Qiao (19743672)Haojie Hu (18793634)Yitong Song (17481129)Chao Wang (146527)Yulin Zhao (273330)MedicinePhysiologyCancerEnvironmental Sciences not elsewhere classifiedBiological Sciences not elsewhere classifiedMathematical Sciences not elsewhere classifiedChemical Sciences not elsewhere classifiedNasal airflowendoscopic nasopharyngectomyrecurrent nasopharyngeal carcinomacomputational fluid dynamicsair conditioning<p>Endoscopic nasopharyngectomy represents a significant intervention for recurrent nasopharyngeal carcinoma (NPC). Various surgical techniques, including transnasal and transoral approaches, are employed. However, the impact of these procedures on nasal airflow dynamics is not well understood. This computational fluid dynamics (CFD) study aimed to investigate alterations in nasal airflow and air conditioning following endoscopic nasopharyngectomy. A 55-year-old male patient with recurrent NPC was selected, whose CT data were utilized for image reconstruction. A preoperative model and two postoperative models, including the transnasal and transoral approach models, were established. The airflow patterns and various CFD parameters were analyzed. In the postoperative models, the high-speed airflow went along the soft palate and into the nasopharyngeal outlet, and there was the low-speed turbulence in the expanded nasopharyngeal cavity. Compared to the preoperative model, the postoperative models exhibited reductions in surface-to-volume ratio, nasal resistance, airflow velocity and proportion of high wall shear stress regions in nasopharynx. The changing trends of nasopharyngeal air temperature and humidity in the preoperative and transoral models were consistent. The heating and humidification efficiency decreased in the transnasal model compared to the transoral model. The endoscopic nasopharyngectomy for recurrent NPC affects the nasal airflow and warming and humidification function. The transoral approach has less influence on aerodynamics of the upper airway compared to the transnasal approach. From a CFD perspective, the endoscopic nasopharyngectomy does not increase the risk of postoperative complications, including the empty nose syndrome and the carotid blowout syndrome.</p>2024-09-26T07:00:03ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.6084/m9.figshare.27108474.v1https://figshare.com/articles/dataset/Alterations_in_nasal_airflow_and_air_conditioning_after_endoscopic_nasopharyngectomy_for_recurrent_nasopharyngeal_carcinoma_a_pilot_computational_fluid_dynamics_study/27108474CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/271084742024-09-26T07:00:03Z |
| spellingShingle | Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study Dong Dong (23216) Medicine Physiology Cancer Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Chemical Sciences not elsewhere classified Nasal airflow endoscopic nasopharyngectomy recurrent nasopharyngeal carcinoma computational fluid dynamics air conditioning |
| status_str | publishedVersion |
| title | Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study |
| title_full | Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study |
| title_fullStr | Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study |
| title_full_unstemmed | Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study |
| title_short | Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study |
| title_sort | Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study |
| topic | Medicine Physiology Cancer Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Chemical Sciences not elsewhere classified Nasal airflow endoscopic nasopharyngectomy recurrent nasopharyngeal carcinoma computational fluid dynamics air conditioning |