Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells.
<p>a. OCR (oxygen consumption rate) and b. AUC for OCR, c. basal respiration, d. maximal respiration, e. acute response and f. ATP-production coupled respiration in INS-1E cells with or without ApoA-I priming (0.1mg/ml, 0.5mg/ml or 1mg/ml) for 2h (n = 5). Each value represents mean ± SD, excep...
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2024
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| _version_ | 1855375017145008128 |
|---|---|
| author | Claire L. Lyons (20234655) |
| author2 | Elaine Cowan (8317896) Oktawia Nilsson (20234658) Manca Mohar (20234661) Pablo Peña-Martínez (20234664) Lena Eliasson (73900) Jens O. Lagerstedt (297275) |
| author2_role | author author author author author author |
| author_facet | Claire L. Lyons (20234655) Elaine Cowan (8317896) Oktawia Nilsson (20234658) Manca Mohar (20234661) Pablo Peña-Martínez (20234664) Lena Eliasson (73900) Jens O. Lagerstedt (297275) |
| author_role | author |
| dc.creator.none.fl_str_mv | Claire L. Lyons (20234655) Elaine Cowan (8317896) Oktawia Nilsson (20234658) Manca Mohar (20234661) Pablo Peña-Martínez (20234664) Lena Eliasson (73900) Jens O. Lagerstedt (297275) |
| dc.date.none.fl_str_mv | 2024-11-15T18:25:21Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pone.0311039.g004 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Effects_of_ApoA1_priming_on_oxidative_phosphorylation_OXPHOS_in_cultured_INS-1E_cells_/27768018 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biophysics Biochemistry Cell Biology Physiology Pharmacology Immunology Cancer Hematology Infectious Diseases Computational Biology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified type 2 diabetes microtubule dynamics 1 scavenger receptor b1 promote insulin secretion increase insulin secretion xlink "> apolipoprotein abca1 depends solely priming via sr insulin secretion receptor pathways unbiased identification triceps experiment primary component performed using mechanisms involved induced increases included control greatly attenuated genes associated fully defined exocytotic pathways density lipoprotein abca1 silencing abca1 pathways |
| dc.title.none.fl_str_mv | Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>a. OCR (oxygen consumption rate) and b. AUC for OCR, c. basal respiration, d. maximal respiration, e. acute response and f. ATP-production coupled respiration in INS-1E cells with or without ApoA-I priming (0.1mg/ml, 0.5mg/ml or 1mg/ml) for 2h (n = 5). Each value represents mean ± SD, except in a where it is mean ± SEM; *p<0.05; paired one-way ANOVA with Dunnett’s posthoc test.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_3cdd9f6bfcc58f3fcefb00a1159685cd |
| identifier_str_mv | 10.1371/journal.pone.0311039.g004 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/27768018 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells.Claire L. Lyons (20234655)Elaine Cowan (8317896)Oktawia Nilsson (20234658)Manca Mohar (20234661)Pablo Peña-Martínez (20234664)Lena Eliasson (73900)Jens O. Lagerstedt (297275)BiophysicsBiochemistryCell BiologyPhysiologyPharmacologyImmunologyCancerHematologyInfectious DiseasesComputational BiologyBiological Sciences not elsewhere classifiedChemical Sciences not elsewhere classifiedInformation Systems not elsewhere classifiedtype 2 diabetesmicrotubule dynamics 1scavenger receptor b1promote insulin secretionincrease insulin secretionxlink "> apolipoproteinabca1 depends solelypriming via srinsulin secretionreceptor pathwaysunbiased identificationtriceps experimentprimary componentperformed usingmechanisms involvedinduced increasesincluded controlgreatly attenuatedgenes associatedfully definedexocytotic pathwaysdensity lipoproteinabca1 silencingabca1 pathways<p>a. OCR (oxygen consumption rate) and b. AUC for OCR, c. basal respiration, d. maximal respiration, e. acute response and f. ATP-production coupled respiration in INS-1E cells with or without ApoA-I priming (0.1mg/ml, 0.5mg/ml or 1mg/ml) for 2h (n = 5). Each value represents mean ± SD, except in a where it is mean ± SEM; *p<0.05; paired one-way ANOVA with Dunnett’s posthoc test.</p>2024-11-15T18:25:21ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pone.0311039.g004https://figshare.com/articles/figure/Effects_of_ApoA1_priming_on_oxidative_phosphorylation_OXPHOS_in_cultured_INS-1E_cells_/27768018CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/277680182024-11-15T18:25:21Z |
| spellingShingle | Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells. Claire L. Lyons (20234655) Biophysics Biochemistry Cell Biology Physiology Pharmacology Immunology Cancer Hematology Infectious Diseases Computational Biology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified type 2 diabetes microtubule dynamics 1 scavenger receptor b1 promote insulin secretion increase insulin secretion xlink "> apolipoprotein abca1 depends solely priming via sr insulin secretion receptor pathways unbiased identification triceps experiment primary component performed using mechanisms involved induced increases included control greatly attenuated genes associated fully defined exocytotic pathways density lipoprotein abca1 silencing abca1 pathways |
| status_str | publishedVersion |
| title | Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells. |
| title_full | Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells. |
| title_fullStr | Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells. |
| title_full_unstemmed | Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells. |
| title_short | Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells. |
| title_sort | Effects of ApoA1 priming on oxidative phosphorylation (OXPHOS) in cultured INS-1E cells. |
| topic | Biophysics Biochemistry Cell Biology Physiology Pharmacology Immunology Cancer Hematology Infectious Diseases Computational Biology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified type 2 diabetes microtubule dynamics 1 scavenger receptor b1 promote insulin secretion increase insulin secretion xlink "> apolipoprotein abca1 depends solely priming via sr insulin secretion receptor pathways unbiased identification triceps experiment primary component performed using mechanisms involved induced increases included control greatly attenuated genes associated fully defined exocytotic pathways density lipoprotein abca1 silencing abca1 pathways |