YqhG is required for systemic virulence but not for <i>in vitro</i> growth.

YqhG is required for systemic virulence but not for <i>in vitro</i> growth.

<p>(A) Growth curves of MRSA wild-type (WT), Δ<i>yqhG</i> mutant, and complemented strain (Δ<i>yqhG</i>-C) cultured in TSB at 37 °C with shaking. (B) Kaplan–Meier survival analysis of BALB/c mice (n = 10 per group) following intravenous infection with 2 × 10⁷ CFU of eac...

Kaydedildi:

Detaylı Bibliyografya
Yazar:	Jianhua Liao (1393228) (author)
Diğer Yazarlar:	Jun Cheng (194158) (author), Baoqing Liu (1508821) (author), Yuzhi Shao (22683349) (author), Chunyan Meng (5993228) (author)
Baskı/Yayın Bilgisi:	2025
Konular:	Medicine Microbiology Cell Biology Biotechnology Evolutionary Biology Ecology Science Policy Infectious Diseases Virology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified therapeutic strategies aimed novel therapeutic approaches murine infection model div >< p defense mechanisms employed conserved gene encoding compromising membrane stability affect biofilm formation staphylococcus aureus </ reduced bacterial burden improved host survival maintaining mrsa ’ oxidative stress resistance yqhg </ withstand host reduced motility oxidative stress increasing resistance stress adaptation potential target periplasmic protein mrsa virulence mrsa pathogenesis key determinant infected organs increased sensitivity imposed stresses growing prevalence findings highlight existing antibiotics critical need attenuates virulence
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller

Optical density measurements of MRSA wild-type, Δ<i>yqhG</i>, and complemented strains during <i>in vitro</i> growth.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Surface motility of the <i>yqhG</i> mutant.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Membrane integrity in the <i>yqhG</i> mutant.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Oxidative stress resistance of the <i>yqhG</i> mutant.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Kidney bacterial burden in mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Heart bacterial burden in mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Survival data of BALB/c mice infected with MRSA wild-type, Δ<i>yqhG</i>, and complemented strains.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Crystal violet quantification of biofilm formation in MRSA wild-type, ΔyqhG, and complemented strains.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Spleen bacterial burden in mice infected with MRSA wild-type, ΔyqhG, and complemented strains.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Liver bacterial burden in mice infected with MRSA wild-type, ΔyqhG, and complemented strains.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Amount of PSMs (μg/1mL culture) in MRSA wild-type, ΔyqhG, and complemented strains.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Quantification of cell-associated PSMs in wild-type, Δ<i>yqhG</i>, and complemented strains. Cell-associated PSMs were extracted from bacterial pellets using 6 M guanidine hydrochloride and quantified by reversed-phase HPLC. The Δ<i>yqhG</i> mutant exhibited a significant reduction in surface-bound PSMs compared with the wild-type strain, whereas complementation restored PSM levels to near wild-type values. Data represent mean ± s.e.m. from three independent experiments. Statistical analysis was performed using one-way ANOVA; *<i>P</i> < 0.05, ns, not significant.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Primers Used in This Study.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Bacterial Strains and Plasmids Used in This Study.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Biofilm formation in MRSA strains.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Viable CFU counts following hydrogen peroxide exposure.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Colony diameter measurements from soft agar motility assays.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

SYTOX Green fluorescence measurements for membrane permeability assessment.
Yazar:: Jianhua Liao (1393228)
Baskı/Yayın Bilgisi: (2025)

Table 1_Hard to jump: host shifts appear unlikely in a T4-like phage evolved in the lab.xlsx
Yazar:: Yu Ning (588573)
Baskı/Yayın Bilgisi: (2025)

Supplementary file 1_Hard to jump: host shifts appear unlikely in a T4-like phage evolved in the lab.docx
Yazar:: Yu Ning (588573)
Baskı/Yayın Bilgisi: (2025)

Protocatechuic Acid alleviates D-gal-induced renal senescence and injury in mice by regulating taurine metabolism
Yazar:: Songhao Tian (22609826)
Baskı/Yayın Bilgisi: (2025)

Table 1_Melatonin mitigates cadmium-induced oxidative damage and modulates polysaccharide biosynthesis in Bletilla striata.xlsx
Yazar:: Deqiong Niu (19691873)
Baskı/Yayın Bilgisi: (2025)

Data Sheet 1_Melatonin mitigates cadmium-induced oxidative damage and modulates polysaccharide biosynthesis in Bletilla striata.docx
Yazar:: Deqiong Niu (19691873)
Baskı/Yayın Bilgisi: (2025)

Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
Yazar:: Wei-hua Yuan (22683169)
Baskı/Yayın Bilgisi: (2025)

Effects of <i>T. gondii</i> infection on rat gut microbiota diversity.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Untargeted serum metabolomics analysis before and after <i>T. gondii</i> infection.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Functional analysis of the intestinal microbial community following <i>T. gondii</i> infection.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Composition of intestinal microbial communities in the large intestine of rats before and after <i>T. gondii</i> infection.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Composition of intestinal microbial communities in the small intestine of rats before and after <i>T. gondii</i> infection.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Differential metabolite results, listing metabolites with significant changes across treatment groups, including fold changes, and <i>p</i>-values.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Correlation network between intestinal bacterial species and differential serum metabolites.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

KEGG pathway enrichment analysis of differential serum metabolites.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Spearman correlation analysis between gut microbial taxa and circulating metabolites, detailing correlation coefficients, significance values, and taxon–metabolite pairings indicative of microbiome–host metabolic interactions.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Orthogonal partial least squares-discriminant analysis (OPLS-DA) of serum metabolomics data.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Quality control assessment of serum metabolomics data.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Heatmap of enriched KEGG pathways across samples, illustrating variations in pathway abundance.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

Graphical abstract.
Yazar:: Ji-Xin Zhao (22056386)
Baskı/Yayın Bilgisi: (2025)

The U sequence method.
Yazar:: Pierre Angelvy (22683450)
Baskı/Yayın Bilgisi: (2025)

Provisional study schedule of MUSIBOT.
Yazar:: Pierre Angelvy (22683450)
Baskı/Yayın Bilgisi: (2025)

Cannot write session to /tmp/vufind_sessions/sess_2nd9cm3ak0s96jdf4csvlj32ap