Filamin A phosphorylation is essential for ORF45-induced detachment and migration but not for virion production.
<p>A-D. HEK293 cells were transfected with Filamin A WT or S2152A mutated constructs and then infected with empty vector or ORF45-expressing lentiviruses at 8 h after transfection. Twenty-four hours later, the cell morphology was observed by inverted microscopy, and representative images are s...
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2025
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