ESL thickness is reduced in Ext1+/-Ext2+/- mice and increased by high sodium diet.

(A) Control mice had a larger ESL (NSD: 0.18±0.04 μm, n = 6; HSD: 0.32±0.05 μm, n = 3) than Ext1+/-Ext2+/- mice on both diets (NSD: 0.04±0.04 μm, n = 6, p = 0.04; HSD 0.07±0.03μm, n = 7, p = 0.004). There was no difference in ESL thickness betwe...

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Bibliographic Details
Main Author:	Rik H. G. Olde Engberink (7109543) (author)
Other Authors:	Judith de Vos (633466) (author), Angela van Weert (633467) (author), Yahua Zhang (7109546) (author), Naomi van Vlies (800568) (author), Bert-Jan H. van den Born (213345) (author), Jens M. Titze (7109549) (author), Ed van Bavel (7109552) (author), Liffert Vogt (162013) (author)
Published:	2019
Subjects:	Medicine Cell Biology Neuroscience Physiology Pharmacology Hematology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified exostosin glycosyltransferase 1 Sodium storage capacity heparan sulfate polymerization genes sodium storage heparan sulfate glycosaminoglycans surface layer thickness volume depletion Ext skin sodium-to-glycosaminoglycan ratio heparan sulfate polymerization Glycosaminoglycans heparan sulfate glycosaminoglycan synthesis blood pressure increase water homeostasis blood pressure response Acute hypertonic saline infusion
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ESL thickness is reduced in Ext1<sup>+/-</sup>Ext2<sup>+/-</sup> mice and increased by high sodium diet.

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