RNAi-based knockdown of RBPs does not have any detectable effect on learning ability.

<p>Boxes signify 3+ RBPs in the same protein family or class (blue box include PUF RBPs, orange box includes CEY RBPs, grey box includes translation initiation machinery). Box and whisker plots are shown for the learning timepoints from the STM/ITM assays for each RBP screened. Box and whisker...

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Bibliographic Details
Main Author:	Ashley N. Hayden (19871128) (author)
Other Authors:	Katie L. Brandel (19871131) (author), Edward W. Pietryk (5777888) (author), Paul R. Merlau (19871134) (author), Priyadharshini Vijayakumar (19871137) (author), Emily J. Leptich (19871140) (author), Elizabeth S. Gaytan (19871143) (author), Meredith I. Williams (19871146) (author), Connie W. Ni (19871149) (author), Hsiao-Tuan Chao (4454008) (author), Jill A. Rosenfeld (9606199) (author), Rachel N. Arey (19871152) (author)
Published:	2024
Subjects:	Biochemistry Neuroscience Pharmacology Evolutionary Biology Immunology Cancer Mental Health Infectious Diseases Biological Sciences not elsewhere classified test evolutionary conservation single nucleotide variants potential new source behavioral screening reveals potential functional significance leveraging human datasets ></ u >< reveal memory regulators div >< p x </ u b </ u identifies ybx dysfunction binding protein required 20 conserved rbps u >< unknown significance rbp dysfunction human genome conserved residue binding proteins ybxs </ ybx3 </ legans </ elegans </ e </ c </ 3 </ study highlights regulate translation rbp family promote memory neurological symptoms neurological phenotypes neurological disorders nervous system memory ability key symptom functionally replace cognitive impairments closest ortholog associative learning 000 rbps
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RNAi-based knockdown of RBPs does not have any detectable effect on learning ability.

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