Data Sheet 1_Genetic reinstatement of RIG-I in chickens reveals insights into avian immune evolution and influenza interaction.docx
<p>Retinoic acid-inducible gene I (RIG-I) activates mitochondrial antiviral signaling proteins, initiating the antiviral response. RIG-I and RNF135, a ubiquitin ligase regulator, are missing in domestic chickens but conserved in mallard ducks. The chickens’ RIG-I loss was long believed to be l...
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2025
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