Data Sheet 1_Genetic reinstatement of RIG-I in chickens reveals insights into avian immune evolution and influenza interaction.docx

Data Sheet 1_Genetic reinstatement of RIG-I in chickens reveals insights into avian immune evolution and influenza interaction.docx

<p>Retinoic acid-inducible gene I (RIG-I) activates mitochondrial antiviral signaling proteins, initiating the antiviral response. RIG-I and RNF135, a ubiquitin ligase regulator, are missing in domestic chickens but conserved in mallard ducks. The chickens’ RIG-I loss was long believed to be l...

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Autor principal: Hicham Sid (8902637) (author)
Outros Autores: Theresa von Heyl (21358229) (author), Sabrina Schleibinger (22389250) (author), Romina Klinger (22389253) (author), Leah Heymelot Nabel (22389256) (author), Hanna Vikkula (22389259) (author), Rodrigo Guabiraba (238152) (author), Vanaique Guillory (10057834) (author), Ryan Scicluna (22389262) (author), Mohanned Naif Alhussien (17829167) (author), Brigitte Böhm (22389289) (author), Benjamin Schade (187193) (author), Daniel Elleder (3245727) (author), Samantha Sives (14288123) (author), Lonneke Vervelde (181449) (author), Sascha Trapp (341020) (author), Benjamin Schusser (488608) (author)
Publicado em: 2025
Assuntos:
Genetic Immunology
avian influenza virus
RIG-I
RNF135
transgenic chicken
duck
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