Figure 2 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

Figure 2 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

<p>Knockdown SIRT3 caused ATF4 protein decrease via translation regulation. <b>A,</b> Western blots show ATF4 protein levels in different DLBCL cells with control or SIRT3 shRNAs. SIRT3 was blotted showing knockdown efficiency, and ACTB was used as reference protein control. <b&...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoir: Meng Li (79487) (author)
Rannpháirtithe: Matthew R. Teater (15129060) (author), Jun Young Hong (6588914) (author), Noel R. Park (15129063) (author), Cihangir Duy (15112006) (author), Hao Shen (195461) (author), Ling Wang (56577) (author), Zhengming Chen (385056) (author), Leandro Cerchietti (15091552) (author), Shawn M. Davidson (14911596) (author), Hening Lin (1306563) (author), Ari M. Melnick (15110132) (author)
Foilsithe / Cruthaithe: 2025
Ábhair:
Cancer
Molecular and Cellular Biology
Cellular Stress Responses
Gene Regulation
Posttranscriptional and translational control
Hematological Cancers
Lymphomas
Metabolism
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