Comparison of integration sites from total CD4 T cells and p24 + cells.

<p>For each participant the number of integration sites (IS) obtained by ISLA from total CD4 T cells and p24 + cells are presented. Grey parts indicate integration sites detected only once and colored parts indicate clonally expanded cells.</p> <p>(TIF)</p>

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Hlavní autor:	Tine Struyve (22683295) (author)
Další autoři:	Marion Pardons (6407921) (author), Jozefien De Clercq (17737815) (author), Liesbet Termote (22683298) (author), Laurens Lambrechts (10532207) (author), Ytse Noppe (22683301) (author), Mathias Lichterfeld (57148) (author), Sofie Rutsaert (10667718) (author), Linos Vandekerckhove (105574) (author)
Vydáno:	2025
Témata:	Biochemistry Medicine Neuroscience Biotechnology Evolutionary Biology Ecology Cancer Infectious Diseases Plant Biology Virology Computational Biology phorbol myristate acetate integration selection mechanisms xlink "> persistence small reservoir sizes treatment initiation timing clonal expansion contributes art ), irrespective individuals treated shortly reservoir persistence early reservoir persistence clonal expansion started treatment pma ), art initiation viral reservoir treated individuals inducible reservoir individuals treated 1 reservoir suggesting post proviruses integrated progressively enriched one year major barrier longitudinal analysis heterochromatin regions five years chronic cohorts cell compartment antiretroviral therapy already detected
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Comparison of integration sites from total CD4 T cells and p24 + cells.

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