Genome instability causes a mitochondrial fission defect.

<p>(<i>A</i>-<i>C</i>) Mitochondrial lengths in body wall muscles in animals with indicated treatments. Each data point represents the mitochondrial length measured from an animal body wall muscle cell. <i>n</i> = 30–40 per group. Median with 95% C. I. Mann-...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Xiaomeng Yang (702951) (author)
مؤلفون آخرون: Ruichen Wei (21181914) (author), Fanfan Meng (8174745) (author), Dianchen Liu (21181917) (author), Xuan Gong (562445) (author), Gary Ruvkun (59736) (author), Wei Wei (21173) (author)
منشور في: 2025
الموضوعات:
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الوصف
الملخص:<p>(<i>A</i>-<i>C</i>) Mitochondrial lengths in body wall muscles in animals with indicated treatments. Each data point represents the mitochondrial length measured from an animal body wall muscle cell. <i>n</i> = 30–40 per group. Median with 95% C. I. Mann-Whitney test. **<i>P</i> < 0.01, *<i>P</i> < 0.05. (<i>D</i>) (Left) Postembryonic cell divisions in animal intestines shown by <i>sur-5</i>::GFP with indicated treatments. Arrows show abnormal karyotypes. (Right) Mitochondrial morphology in a single body wall muscle cell in animals with indicated treatments. Scale bar, 5 μm. (<i>E</i>) TOM20 peak number for the plot profiles of mitochondrial morphology (left, Mean ± s.d.), and mitochondrial lengths body wall muscles (right, Median with 95% C. I. Mann-Whitney test) in animals with indicated treatments. ****<i>P</i> < 0.0001, ***<i>P</i> < 0.001. (<i>F</i>-<i>I</i>) P<i>hsp-6</i>::GFP expression in animals with indicated treatments. Each data point represents the fluorescence intensity measured from a single animal. <i>n</i> > 15 per group.</p> <p>(TIF)</p>