Validation of IDRAS on an oscillating setpoint in a kinetic model.

Validation of IDRAS on an oscillating setpoint in a kinetic model.

<p>(a) Illustration of the regulated gene expression feedback-loop model. mRNA <i>M</i>, produced at a rate <i>K</i>(<i>t</i>), induces the production of proteins <i>S</i> and <i>P</i> and receives a negative feedback of their sum. Si...

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Bibliographic Details
Main Author:	Ron Teichner (21492434) (author)
Other Authors:	Naama Brenner (28701) (author), Ron Meir (59392) (author)
Published:	2025
Subjects:	Genetics Biotechnology Developmental Biology Cancer Mental Health Hematology Infectious Diseases Computational Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Information Systems not elsewhere classified realistic biological models nutrient availability fluctuates internally regulated variables identified variables regulated dynamic reference value studying biological regulation inducing oscillatory dynamics identifying dynamic regulation driven algorithm capable control objectives based dynamic set regulation system regulation set simulation data previous algorithm prediction component novel data internal perturbations inducing time important challenge fixed set first algorithm empirical data also predicts
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