Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies

<p>Supplementary Figure 5 A. Heat map of Spearman's correlation coefficients among paired proteins in the bone marrow (BM) supernatant and peripheral blood (PB) serum of 16 patients with WM (n=11) and IgM MGUS (n=5). Positive correlations are shown in red, whereas negative correlations ar...

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Egile nagusia: Patrizia Mondello (15045002) (author)
Beste egile batzuk: Jonas Paludo (15054545) (author), Joseph P. Novak (15054548) (author), Kerstin Wenzl (15054551) (author), Zhi-Zhang Yang (15054554) (author), Shahrzad Jalali (15054557) (author), Jordan E. Krull (15052337) (author), Esteban Braggio (15054560) (author), Surendra Dasari (15054563) (author), Michelle K. Manske (15054566) (author), Jithma A. Abeykoon (15054569) (author), Vivekananda Sarangi (15054572) (author), Prashant Kapoor (15054575) (author), Aneel Paulus (15051696) (author), Craig B. Reeder (15054578) (author), Sikander Ailawadhi (15051765) (author), Asher A. Chanan-Khan (15054581) (author), Robert A. Kyle (15054584) (author), Morie A. Gertz (15054587) (author), Anne J. Novak (15054590) (author), Stephen M. Ansell (15037529) (author)
Argitaratua: 2025
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_version_ 1849927633347805184
author Patrizia Mondello (15045002)
author2 Jonas Paludo (15054545)
Joseph P. Novak (15054548)
Kerstin Wenzl (15054551)
Zhi-Zhang Yang (15054554)
Shahrzad Jalali (15054557)
Jordan E. Krull (15052337)
Esteban Braggio (15054560)
Surendra Dasari (15054563)
Michelle K. Manske (15054566)
Jithma A. Abeykoon (15054569)
Vivekananda Sarangi (15054572)
Prashant Kapoor (15054575)
Aneel Paulus (15051696)
Craig B. Reeder (15054578)
Sikander Ailawadhi (15051765)
Asher A. Chanan-Khan (15054581)
Robert A. Kyle (15054584)
Morie A. Gertz (15054587)
Anne J. Novak (15054590)
Stephen M. Ansell (15037529)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Patrizia Mondello (15045002)
Jonas Paludo (15054545)
Joseph P. Novak (15054548)
Kerstin Wenzl (15054551)
Zhi-Zhang Yang (15054554)
Shahrzad Jalali (15054557)
Jordan E. Krull (15052337)
Esteban Braggio (15054560)
Surendra Dasari (15054563)
Michelle K. Manske (15054566)
Jithma A. Abeykoon (15054569)
Vivekananda Sarangi (15054572)
Prashant Kapoor (15054575)
Aneel Paulus (15051696)
Craig B. Reeder (15054578)
Sikander Ailawadhi (15051765)
Asher A. Chanan-Khan (15054581)
Robert A. Kyle (15054584)
Morie A. Gertz (15054587)
Anne J. Novak (15054590)
Stephen M. Ansell (15037529)
author_role author
dc.creator.none.fl_str_mv Patrizia Mondello (15045002)
Jonas Paludo (15054545)
Joseph P. Novak (15054548)
Kerstin Wenzl (15054551)
Zhi-Zhang Yang (15054554)
Shahrzad Jalali (15054557)
Jordan E. Krull (15052337)
Esteban Braggio (15054560)
Surendra Dasari (15054563)
Michelle K. Manske (15054566)
Jithma A. Abeykoon (15054569)
Vivekananda Sarangi (15054572)
Prashant Kapoor (15054575)
Aneel Paulus (15051696)
Craig B. Reeder (15054578)
Sikander Ailawadhi (15051765)
Asher A. Chanan-Khan (15054581)
Robert A. Kyle (15054584)
Morie A. Gertz (15054587)
Anne J. Novak (15054590)
Stephen M. Ansell (15037529)
dc.date.none.fl_str_mv 2025-11-25T13:05:09Z
dc.identifier.none.fl_str_mv 10.1158/1078-0432.30707255
dc.relation.none.fl_str_mv https://figshare.com/articles/figure/Supplementary_Figure_5_from_Molecular_Clusters_and_Tumor-Immune_Drivers_of_IgM_Monoclonal_Gammopathies/30707255
dc.rights.none.fl_str_mv CC BY
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cancer
Tumor Biology
Therapeutic Research and Development
Hematological Cancers
Translational Research
Tumor Heterogeneity
Tumor Microenvironment
dc.title.none.fl_str_mv Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies
dc.type.none.fl_str_mv Image
Figure
info:eu-repo/semantics/publishedVersion
image
description <p>Supplementary Figure 5 A. Heat map of Spearman's correlation coefficients among paired proteins in the bone marrow (BM) supernatant and peripheral blood (PB) serum of 16 patients with WM (n=11) and IgM MGUS (n=5). Positive correlations are shown in red, whereas negative correlations are indicated in blue. B. Heat maps showing expression of (i) 12 proteins significantly different between C1 vs C2 plus C3, and (i) 74 proteins significantly different between C2 vs C1 plus C3 in the PB serum. The left bar shows correlation coefficients between BM and PB proteins. Gray squares indicate non significance.</p>
eu_rights_str_mv openAccess
id Manara_441bbee16ce29bfc0a9af81201b3d2e0
identifier_str_mv 10.1158/1078-0432.30707255
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30707255
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY
spelling Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal GammopathiesPatrizia Mondello (15045002)Jonas Paludo (15054545)Joseph P. Novak (15054548)Kerstin Wenzl (15054551)Zhi-Zhang Yang (15054554)Shahrzad Jalali (15054557)Jordan E. Krull (15052337)Esteban Braggio (15054560)Surendra Dasari (15054563)Michelle K. Manske (15054566)Jithma A. Abeykoon (15054569)Vivekananda Sarangi (15054572)Prashant Kapoor (15054575)Aneel Paulus (15051696)Craig B. Reeder (15054578)Sikander Ailawadhi (15051765)Asher A. Chanan-Khan (15054581)Robert A. Kyle (15054584)Morie A. Gertz (15054587)Anne J. Novak (15054590)Stephen M. Ansell (15037529)CancerTumor BiologyTherapeutic Research and DevelopmentHematological CancersTranslational ResearchTumor HeterogeneityTumor Microenvironment<p>Supplementary Figure 5 A. Heat map of Spearman's correlation coefficients among paired proteins in the bone marrow (BM) supernatant and peripheral blood (PB) serum of 16 patients with WM (n=11) and IgM MGUS (n=5). Positive correlations are shown in red, whereas negative correlations are indicated in blue. B. Heat maps showing expression of (i) 12 proteins significantly different between C1 vs C2 plus C3, and (i) 74 proteins significantly different between C2 vs C1 plus C3 in the PB serum. The left bar shows correlation coefficients between BM and PB proteins. Gray squares indicate non significance.</p>2025-11-25T13:05:09ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/1078-0432.30707255https://figshare.com/articles/figure/Supplementary_Figure_5_from_Molecular_Clusters_and_Tumor-Immune_Drivers_of_IgM_Monoclonal_Gammopathies/30707255CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/307072552025-11-25T13:05:09Z
spellingShingle Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies
Patrizia Mondello (15045002)
Cancer
Tumor Biology
Therapeutic Research and Development
Hematological Cancers
Translational Research
Tumor Heterogeneity
Tumor Microenvironment
status_str publishedVersion
title Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies
title_full Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies
title_fullStr Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies
title_full_unstemmed Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies
title_short Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies
title_sort Supplementary Figure 5 from Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies
topic Cancer
Tumor Biology
Therapeutic Research and Development
Hematological Cancers
Translational Research
Tumor Heterogeneity
Tumor Microenvironment