Circoplots of two representative loci.

<p>Region plots for two novel pain risk loci as representative of those associated with multiple pain traits (A) vs. those with greater trait specificity (B). A. Locus associated with both Headache/Migraine and Muscular pain centered on chromosome 3q26.31 at the UTR5 of <i>NLGN1</i>...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Evelina Mocci (374296) (author)
مؤلفون آخرون:	Kathryn Ward (17174753) (author), James A. Perry (10515389) (author), Angela Starkweather (10581244) (author), Laura S. Stone (9392671) (author), Siobhan M. Schabrun (11929656) (author), Cynthia Renn (17174756) (author), Susan G. Dorsey (11780093) (author), Seth A. Ament (9427801) (author)
منشور في:	2023
الموضوعات:	Cell Biology Genetics Physiology Ecology Immunology Biological Sciences not elsewhere classified public health system growing opioid crisis immunological traits mediate genetic relationship among remaining 34 loci overlap loci identified wide association studies chronic pain compared loci primarily associated loci associated related traits genetic correlation risk loci loci fall 99 loci united states uk biobank specific pain skeletomuscular pain significant burden related pain pleiotropic relationships pain susceptibility multiple forms joint analysis inflammatory pathways healthy controls genomic proximity genes involved four categories epidemic proportions earlier studies chromatin interaction applied leave 664 genes
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Circoplots of two representative loci.

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